Barbiturates increase the rate of metabolism of:

Correct Answer: D

Rationale: The correct answer is D: All of the above. Barbiturates are known to increase the metabolism of various drugs, including anticoagulants, digitalis compounds, and glucocorticoids. This is because barbiturates induce liver enzymes responsible for drug metabolism, leading to faster clearance of these medications from the body. Therefore, the correct answer is D as barbiturates can affect the metabolism of all the mentioned drug classes. Choices A, B, and C are incorrect as barbiturates do not selectively increase the metabolism of only one of these drug classes, but rather have a broad impact on drug metabolism.

Correct Answer: B

Rationale: The correct answer is B: Bromocriptine. Bromocriptine is a dopamine agonist that can reduce prolactin levels by stimulating dopamine receptors in the pituitary gland. This makes it effective in treating hyperprolactinemia. Benztropine (A) is an anticholinergic used for Parkinson's symptoms, not hyperprolactinemia. Amantadine (C) is an antiviral and weak dopamine agonist primarily used for Parkinson's. Levodopa (D) is a precursor to dopamine and is used for Parkinson's symptoms but not hyperprolactinemia.

Correct Answer: C

Rationale: The correct answer is C: Alcohol increases body heat loss. When alcohol is consumed, it causes blood vessels near the skin to dilate, resulting in increased blood flow to the skin's surface. This leads to heat being lost from the body, causing a drop in core body temperature. Choices A and B are incorrect because alcohol actually decreases body temperature by increasing heat loss. Choice D is also incorrect because alcohol does affect body temperature by promoting heat loss.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Butyrophenone derivatives are a class of antipsychotic drugs. 2. Droperidol is a butyrophenone derivative, used for sedation and treating psychosis. 3. Thioridazine, Sertindole, and Fluphenazine are not butyrophenone derivatives. 4. Therefore, the correct answer is A, Droperidol. In summary: - A (Droperidol) is correct as it belongs to the butyrophenone derivative class. - B (Thioridazine), C (Sertindole), and D (Fluphenazine) are incorrect as they are not butyrophenone derivatives.

Correct Answer: B

Rationale: Rationale: Amitriptyline is a tricyclic antidepressant with strong antimuscarinic effects due to its chemical structure. The tertiary amine group increases antimuscarinic activity. Desipramine (A) is also a tricyclic antidepressant but has lower antimuscarinic effects. Trazodone (C) and Mirtazapine (D) are not tricyclic antidepressants, hence have minimal antimuscarinic effects compared to Amitriptyline.