Bacteriological laboratory examines canned meat whether it contains botulinum toxin. For this purpose an extract of test specimen and antitoxic antibotulinic serum of A, B, E types were introduced to a group of mice under examination; a control group of mice got the extract without antibotulinic serum. What serological reaction was applied?

Correct Answer: A

Rationale: The correct answer is A: Neutralization. In this scenario, the antibotulinic serum of types A, B, and E were introduced to neutralize the botulinum toxin in the test specimen. The serological reaction applied here involves the neutralization of the toxin by the specific antibodies present in the serum. This process prevents the toxin from causing harm to the mice. Summary of other choices: B: Precipitation - This involves the formation of insoluble complexes between antigen and antibody, not the specific neutralization seen in this case. C: Complement binding - This involves activation of the complement system leading to cell lysis, not the direct neutralization of toxin. D: Double immune diffusion - This technique is used to determine the presence of specific antibodies or antigens based on their diffusion patterns, not the neutralization of toxin as seen in this scenario.

Correct Answer: B

Rationale: The correct answer is B because sterilization is the process of completely destroying all microorganisms, including resistant forms like spores, ensuring no viable organisms remain. This is crucial for ensuring complete elimination of potential pathogens. Choice A is incorrect because sterilization should eliminate all microorganisms, including spores. Choice C is incorrect as it describes disinfection, not sterilization. Choice D is incorrect because sterilization aims to eradicate all microorganisms, not leave any viable ones behind.

Correct Answer: C

Rationale: Rationale: 1. Vibrio cholerae produces cholera toxin causing severe diarrhea. 2. Clostridium tetani causes tetanus, not diarrhea. 3. Clostridium botulinum causes botulism, not diarrhea. 4. Shigella dysenteriae causes dysentery, not typical diarrhea. Summary: A: Incorrect, causes tetanus. B: Incorrect, causes botulism. C: Correct, produces cholera toxin causing severe diarrhea. D: Incorrect, causes dysentery.

Correct Answer: A

Rationale: The correct answer is A: Hyperresponsiveness reaction type IV. This type of reaction, also known as delayed-type hypersensitivity, is characterized by the activation of T lymphocytes and macrophages, leading to inflammation at the site of antigen exposure. In the case of the Mantoux test, the appearance of a papule 48 hours later indicates a delayed hypersensitivity reaction mediated by T cells. Choice B: Reaction of Arthus phenomenon type is incorrect as this type of reaction involves immune complexes forming in the blood vessels leading to tissue damage, which is not the mechanism seen in the Mantoux test reaction. Choice C: Reaction of serum sickness type is incorrect as this type of reaction involves the formation of immune complexes in the blood leading to systemic symptoms like fever, rash, and joint pain, which is not typically seen in the Mantoux test reaction. Choice D: Atopic reaction is incorrect as atopic reactions involve IgE antibodies and mast cell degranulation, which are not the mechanisms

Correct Answer: A

Rationale: Step-by-step rationale: 1. IgG is the most abundant immunoglobin in a normal healthy adult due to its long half-life and diverse functions. 2. It plays a crucial role in immune response by neutralizing pathogens and enhancing phagocytosis. 3. IgA is mainly found in mucosal areas, IgE is involved in allergic reactions, and IgD's function is not fully understood. 4. Therefore, IgG is the correct answer as it is the predominant immunoglobin in circulation, providing broad immune protection.

Correct Answer: B

Rationale: The correct answer is B: BCG. Bacille Calmette-Guérin (BCG) vaccine is used for the prevention of tuberculosis. BCG is a live attenuated strain of Mycobacterium bovis that helps the immune system recognize and fight off tuberculosis bacteria. Specific anti-tuberculosis serum (A) is not used for prevention but for treatment. DTP (C) stands for diphtheria, tetanus, and pertussis vaccine, not specific for tuberculosis prevention. PPD (D) is a tuberculin skin test used for diagnosis, not prevention. Thus, BCG is the correct choice for tuberculosis prevention.

Correct Answer: B

Rationale: The correct answer is B: For HIV. Pneumocystis pneumonia in a young man with CD4+ cells less than 200/mm3 is highly suggestive of HIV infection. HIV weakens the immune system, leading to opportunistic infections like pneumocystis pneumonia. Testing for HIV is crucial for diagnosis and appropriate management. Explanation for other choices: A: Testing for ureaplasma urealyticum is not indicated in this case as the symptoms and CD4+ cell count point towards an HIV-related infection. C: Testing for Treponema pallidum (syphilis) is not relevant in the context of a young man with pneumocystis pneumonia and low CD4+ cell count. D: Testing for Neisseria gonorrhoea is not appropriate in this scenario as the symptoms and CD4+ cell count suggest an underlying HIV infection rather than a bacterial sexually transmitted infection.

Correct Answer: B

Rationale: The correct answer is B: Agglutination. During a suspected plague outbreak, agglutination testing is used to quickly identify the antigen of the causative agent. In this test, specific antibodies are added to a sample containing the suspected antigen. If the antigen is present, it will clump together (agglutinate) with the antibodies, indicating a positive result. This method is rapid and efficient for identifying the presence of the plague-causing agent. Choice A: Precipitation involves the formation of a visible precipitate when antigen and antibody react, but it is not as quick or specific as agglutination for identifying the antigen in this scenario. Choice C: Passive hemagglutination is a variation of agglutination that uses red blood cells as carriers for antigens or antibodies. While it can be useful in certain situations, it is not typically the first choice for rapid identification of plague antigen. Choice D: Complement binding is a different type of

Correct Answer: C

Rationale: The correct answer is C: green monkeys. The Marburg virus was first identified in 1967 in Marburg and Frankfurt, Germany, after outbreaks in lab workers exposed to infected African green monkeys. These monkeys were imported from Uganda. The virus is believed to be originally endemic in certain species of African bats and is transmitted to humans through contact with infected animals. Choice A, laboratory rats, is incorrect as the virus did not originate from rats. Choice B, birds, and Choice D, wild turkeys, are also incorrect as there is no evidence linking these animals to the transmission of the Marburg virus.