ATI RN
ATI RN Pharmacology Online Practice 2023 B Questions
Question 1 of 5
Bactericidal action are elicited by the following, except:
Correct Answer: C
Rationale: Nystatin is an antifungal medication used to treat fungal infections caused by yeast. It works by binding to ergosterol, a component of fungal cell membranes, causing them to become porous and leaky, ultimately leading to the death of the fungus. Nystatin does not have bactericidal action because it specifically targets fungal cells and is not effective against bacteria.
Question 2 of 5
The most potent of ester type of Local Anesthesia:
Correct Answer: B
Rationale: Articaine is considered the most potent ester type of local anesthetic. It is known for its high efficacy in providing profound anesthesia due to its unique chemical structure that enhances its ability to penetrate tissues effectively. Articaine also has a rapid onset of action and a relatively long duration of action compared to other ester local anesthetics. These characteristics make it a popular choice for various dental and medical procedures where deep and long-lasting anesthesia is required.
Question 3 of 5
A 43-year-old woman with multiple sclerosis has not been treated with medication because of only having mild symptoms. Now, she has bilateral lower extremity weakness and urinary complaints. She has begun on mitoxantrone. Which of the following adverse effects must the treating physician be aware of?
Correct Answer: B
Rationale: Mitoxantrone for MS progression risks hepatitis . This chemotherapeutic damages liver cells, requiring monitoring. Anxiety , hypopyrexia , muscle strength , and leukocytosis (E) aren't primary. Hepatotoxicity, with cardiotoxicity, is a key concern in this worsening MS case.
Question 4 of 5
The most common dose-limiting toxicity of chemotherapy is:
Correct Answer: C
Rationale: Myelosuppression, the suppression of bone marrow activity, is the most common dose-limiting toxicity of chemotherapy. It leads to reduced production of blood cells, including white blood cells, red blood cells, and platelets, increasing the risk of infections, anemia, and bleeding. While nausea, vomiting, and mucositis are significant side effects, they can often be managed with supportive care. Myelosuppression, however, can be life-threatening and frequently requires dose adjustments or delays in treatment. Bloody stools are less common and typically not the primary dose-limiting factor.
Question 5 of 5
A 38-year-old man who is obese complains of an extremely painful, swollen metatarsophalangeal joint of his left big toe. He presents to his primary care physician for evaluation. He has had two similar attacks in the past 4 years. The physician prescribes probenecid. Which of the following describes probenecid's mechanism of action?
Correct Answer: C
Rationale: Gout (recurrent toe pain) is treated with probenecid , which inhibits urate reabsorption in the proximal tubule, increasing uric acid excretion. Anti-inflammatory and leukocyte migration inhibition are colchicine's effects. Xanthine oxidase inhibition is allopurinol's. Upregulation (E) is wrong. Probenecid's uricosuric action reduces urate levels, preventing attacks.