ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
Bacteria such as Mycobacterium tuberculosis have acquired the capacity to inhibit phagosome-lysosome fusion. What is a consequence of this?
Correct Answer: A
Rationale: Inhibiting phagosome-lysosome fusion reduces peptide generation for MHC Class II presentation, lowering surface expression.
Question 2 of 5
Critical in antigen-capture and uptake in peripheral tissues
Correct Answer: D
Rationale: Dendritic cells capture and present antigens in tissues.
Question 3 of 5
The spleen has a red pulp (macrophages and red blood cells) and a white pulp (dense lymphoid tissue). T cells are found chiefly in the and B cells are found in the both within the pulp.
Correct Answer: A
Rationale: T cells are in PALS, B cells in follicles, both in white pulp.
Question 4 of 5
lymphocytes migrate to and lodge in selected tissue sites (lymphocyte homing). constantly circulate among the lymphoid organs until they encounter antigen or die.
Correct Answer: B
Rationale: Memory T cells home to tissues; naïve T cells circulate through secondary lymphoid organs.
Question 5 of 5
During B cell development, at what stage is membrane bound IgM found?
Correct Answer: D
Rationale: Membrane-bound IgM is expressed on immature B cells.