ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
B cells whose BCRs bind antigen with high-affinity receive survival signals (called selection) from follicular dendritic cells (FDCs) and germinal center T cells, whereas those that fail to bind antigen
Correct Answer: B
Rationale: High-affinity B cells undergo positive selection and survive; low-affinity cells die.
Question 2 of 5
Cytokines produced by TH1 are ___ (microbial infection response) and cytokines produced by TH2 are ___ (parasitic infection response and allergy response).
Correct Answer: A
Rationale: TH1 produces IFN-γ and TNF-β for microbial defense; TH2 produces IL-4 and IL-5 for parasites/allergies.
Question 3 of 5
Which of the following best describes the affinity of antibody secreted for effector B cells?
Correct Answer: C
Rationale: Affinity increases during the immune response due to affinity maturation in effector B cells.
Question 4 of 5
Surfactants, pathogen binding collectins
Correct Answer: D
Rationale: Surfactants and collectins are found in the lower respiratory tract as innate defenses.
Question 5 of 5
Which of the following component molecules is activated in the classical pathway after binding to an Fc?
Correct Answer: A
Rationale: C1 binds to the Fc region of antibodies to initiate the classical pathway.