ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
B cell co-receptor phosphorylation sites include Igα/Igβ and which of the following?
Correct Answer: A
Rationale: CD19 contains phosphorylation sites critical for amplifying BCR signaling.
Question 2 of 5
In the adult, the primary lymphoid organs, whose cells expand clonally, are the and secondary lymphoid organs, which create effector cells, are the , as well as mucosa associated lymphoid tissue (MALT) lining the respiratory, GI, and reproductive tracts.
Correct Answer: B
Rationale: Primary lymphoid organs are bone marrow and thymus; secondary are spleen, lymph nodes, and MALT.
Question 3 of 5
Regarding mucosa-associated lymphoid tissue (MALT), which of the following is secreted by B cells across the epithelium?
Correct Answer: A
Rationale: IgA is the primary antibody secreted across mucosal epithelium.
Question 4 of 5
During B cell development, when is there rearrangement in the heavy (H) chain of the immunoblobulin gene started?
Correct Answer: A
Rationale: Heavy chain rearrangement begins in the pro-B cell stage.
Question 5 of 5
The activation of a naïve B cell, which generally requires a second accessory signal, occurs when the B cell exits the bloodstream and into a lymphoid organ, meets antigen, internalizes the BCR-antigen complex, and eventually becomes cells.
Correct Answer: C
Rationale: Naïve B cell activation in primary response produces plasma and memory cells.