B-cell antigen receptors can interact directly with antigen, whereas T-cell antigen receptors only recognize antigen when it is presented to them on the surface of another cell.

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NCLEX Pediatric Immunization Questions Questions

Question 1 of 5

B-cell antigen receptors can interact directly with antigen, whereas T-cell antigen receptors only recognize antigen when it is presented to them on the surface of another cell.

Correct Answer: A

Rationale: B-cell receptors (BCRs) bind free antigens directly, while T-cell receptors (TCRs) require antigen presentation via MHC molecules on another cell's surface.

Question 2 of 5

Neutrophils

Correct Answer: D

Rationale: Neutrophils are primary phagocytes that engulf and kill bacteria using bactericidal mechanisms.

Question 3 of 5

Which of the following types of antigen presenting cells (APCs) is critical in uptake and presentation of antigen to T cells?

Correct Answer: D

Rationale: All three (macrophages, dendritic cells, B cells) are APCs critical for antigen uptake and presentation to T cells; since E is moved to D, D is correct for all.

Question 4 of 5

The genes encoding which of the following are extensively polymorphic (have multiple alleles or forms of the same gene)?

Correct Answer: C

Rationale: MHC genes are highly polymorphic, providing diverse antigen presentation across populations, unlike BCR or TCR genes.

Question 5 of 5

Which of the following best describes penicillin, a hapten?

Correct Answer: D

Rationale: Penicillin is a small hapten that requires conjugation to a carrier protein to elicit an immune response.

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