ATI RN
Pediatric Genetics Questions
Question 1 of 5
Autosomes:
Correct Answer: A
Rationale: Autosomes are the non-sex chromosomes (1-22 in humans), distinguishing them from sex chromosomes (X and Y).
Question 2 of 5
John and Jesica are planning a family, but since each has a brother who has sickle cell anemia, they are concerned that their children may develop sickle-cell disease. Neither John, Jane nor their respective parents have the disease. They consult a genetic counselor who tells them:
Correct Answer: D
Rationale: Sickle cell anemia is autosomal recessive. Both John and Jesica are likely carriers (1/2 chance each, given affected siblings and unaffected parents). Risk of an affected child is 1/4 if both are carriers, but testing is needed to confirm carrier status.
Question 3 of 5
A linkage map:
Correct Answer: A
Rationale: A linkage map uses recombination frequencies to determine the relative order of genes on a chromosome.
Question 4 of 5
Disorders involving unusual numbers of sex chromosomes show that maleness is caused by the:
Correct Answer: B
Rationale: The Y chromosome’s SRY gene determines maleness, as seen in conditions like 47,XXY (male) vs. 45,X (female).
Question 5 of 5
Cancer cells:
Correct Answer: C
Rationale: Cancer cells proliferate uncontrollably and can become immortal (e.g., HeLa cells), evading normal cell death.