ATI RN
ATI Capstone Pharmacology Assessment 2 Quizlet Questions
Question 1 of 5
As you are preparing morning medications, the patient says, 'I have had loose stools all night long.' Your patient has scheduled docusate at 0900. What is the priority action?
Correct Answer: A
Rationale: Docusate is a stool softener used to prevent constipation. If the patient is already experiencing loose stools, administering docusate could exacerbate the condition, leading to diarrhea or dehydration. The nurse should hold the medication and inform the healthcare provider to reassess the need for docusate. Increasing the IV flow rate (C) or the dose (D) is inappropriate in this situation.
Question 2 of 5
A nurse is giving dietary instructions to a client receiving levodopa. Which of the following food items should be avoided by the client?
Correct Answer: A
Rationale: Goat yogurt and other high-protein foods should be avoided when taking levodopa because protein can interfere with the absorption of the medication, reducing its effectiveness. Whole grain cereal, asparagus, and apples are not known to interact with levodopa. Therefore, goat yogurt is the food item to avoid.
Question 3 of 5
Which of the following is the systemic treatment of choice for female hirsutism?
Correct Answer: D
Rationale: Hirsutism involves excess androgen-driven hair growth. Tamoxifen, an estrogen modulator, treats breast cancer, not hirsutism. Ethinylestradiol reduces androgens via SHBG increase, but alone isn't optimal. Norethisterone, a progestin, may worsen hirsutism. Finasteride blocks 5-alpha-reductase, reducing DHT, but cyproterone, an anti-androgen, directly inhibits androgen receptors and gonadotropin release, the systemic choice for hirsutism (e.g., in PCOS). Its potency targets the root cause, offering effective hair reduction.
Question 4 of 5
Regarding antibiotic resistance:
Correct Answer: B
Rationale: Beta-lactamase isn't the primary resistance mechanism in pneumococci (PBP alteration is), so that's false. Penicillin's poor penetration into gram-negative bacteria due to outer membranes is a true statement, a common resistance factor. Altered penicillin-binding proteins (PBPs) drive pneumococcal resistance, not the main general mechanism, though true in context. Methicillin resistance in Staph (MRSA) is due to mecA gene producing altered PBPs, not just beta-lactamase, so that's false. Penetration issues in gram-negatives are a fundamental barrier, guiding beta-lactam design like piperacillin.
Question 5 of 5
The physician ordered a brand name drug for the client, paroxetine (Paxil). After taking this medication for a year, the client tells the nurse that it is no longer working. What is the best assessment of the nurse at this time?
Correct Answer: B
Rationale: Paroxetine's effectiveness waning after a year suggests possible drug interactions reducing its levels or efficacy, a common issue needing assessment via medication review. Needing a change assumes a conclusion without evidence. Paxil and paroxetine are the same (brand vs. generic), making that question moot. Beck assessment evaluates depression, not drug failure. Interactions align with pharmacokinetic principles, offering a proactive step to identify culprits like enzyme inducers, critical for adjusting therapy.