ATI RN
ATI Proctored Pharmacology Quizlet Questions
Question 1 of 5
Approximately how many milligrams of aspirin are contained in 5grams tablet?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
What are the therapeutic and adverse effects associated with the adrenergic blocking agents related to?
Correct Answer: A
Rationale: The therapeutic and adverse effects associated with these drugs are related to their adrenergic-receptor-site specificity; that is, the ability to react with specific adrenergic receptor sites without activating them, thus preventing the typical manifestations of sympathetic nervous system (SNS) activation. By occupying the adrenergic receptor site, they prevent norepinephrine released from the nerve terminal or from the adrenal medulla from activating the receptor, thus blocking the SNS effects. The nurse should understand the mechanism of action of adrenergic blocking agents to ensure safe and effective administration.
Question 3 of 5
The nurse is administering oxycodone to a patient. Which common side effect should the nurse teach the patient about?
Correct Answer: D
Rationale: Drowsiness is a common side effect of oxycodone, an opioid analgesic. Patients should be advised to avoid activities requiring alertness, such as driving, while taking this medication. Paresthesia (A), increased intracranial pressure (B), and occipital headache (C) are not typical side effects of oxycodone.
Question 4 of 5
A client with rheumatoid arthritis has been receiving hydroxychloroquine (Plaquenil) in recent months. The nurse tells the client to visit which of the following while on the treatment?
Correct Answer: B
Rationale: Hydroxychloroquine can cause retinal toxicity, leading to vision loss. Regular ophthalmologic examinations are essential to detect early signs of toxicity. While dental, pulmonary, and endocrine health are important, they are not directly related to hydroxychloroquine's side effects. Monitoring for retinal changes is critical to ensure the safe use of this medication.
Question 5 of 5
Which of the following is the antidote of first choice in the treatment of potentially fatal paracetamol overdose?
Correct Answer: B
Rationale: Paracetamol overdose risks fatal hepatotoxicity via NAPQI, a toxic metabolite depleting glutathione. Methionine replenishes glutathione orally, effective if given early, but less preferred due to slower action and GI upset. Acetylcysteine, administered IV or orally, directly supplies glutathione precursors, neutralizing NAPQI within the critical 8-12 hour window, making it the first-choice antidote per global guidelines (e.g., Rumack-Matthew nomogram). It's superior for its rapid efficacy, especially beyond 8 hours, preventing liver failure. Naloxone reverses opioids, irrelevant here. Dicobalt edetate treats cyanide poisoning, not paracetamol. Flumazenil targets benzodiazepines. Acetylcysteine's mechanism and timing flexibility ensure maximal survival, critical in emergency settings where overdose severity varies.