Any child with diabetic ketoacidosis (DKA) can be easily transitioned to oral intake and subcutaneous insulin when the following criteria are found EXCEPT

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Pediatric Endocrine System Questions

Question 1 of 5

Any child with diabetic ketoacidosis (DKA) can be easily transitioned to oral intake and subcutaneous insulin when the following criteria are found EXCEPT

Correct Answer: B

Rationale: Transition requires pH >7.30 (not 7.25, B) to ensure acidosis resolution.

Question 2 of 5

When diabetes and thyroid disease coexist, the possibility of autoimmune adrenal insufficiency should be considered. It may be heralded by the followings EXCEPT

Correct Answer: A

Rationale: Increasing insulin requirements (A) suggest better insulin sensitivity, not adrenal insufficiency, which reduces insulin needs.

Question 3 of 5

You suspect a metabolic problem in a 30-day-old girl presented with poor feeding, vomiting, lethargy, and convulsion. Previous sibling died with the same condition. Serum ammonia, pH, HCO3, and anion gap are normal. Of the following, the MOST likely diagnosis is

Correct Answer: D

Rationale: Normal ammonia, pH, and anion gap with neonatal symptoms and family history suggest an aminoacidopathy (e.g., nonketotic hyperglycinemia), not porphyria (A), galactosemia (B), organic acidemia (C), or urea cycle defect (D), which alter these parameters.

Question 4 of 5

A 4-month-old boy presented with failure to thrive, rapid breathing, and repeated vomiting. On examination, there is hepatomegaly and abdominal sonography revealed renal calcification. Of the following, the MOST likely urine odor of this infant is

Correct Answer: D

Rationale: Tyrosinemia type 1, with hepatomegaly, failure to thrive, and renal issues, produces a boiled cabbage urine odor from tyrosine metabolites, unlike other disorders (A, B, C, E).

Question 5 of 5

The following are ocular manifestations of albinism EXCEPT

Correct Answer: D

Rationale: Albinism causes red reflex (A), strabismus (B), refractive errors (C), and poor binocular vision (E) due to hypopigmentation and foveal hypoplasia, not hyperplasia (D), which is the opposite.

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