ATI RN
Burns Pediatric Primary Care Test Bank Questions
Question 1 of 5
Antimetabolites are a diverse group of antineoplastic agents that interfere with various metabolic actions of the cell. The mechanism of action of antimetabolites interferes with:
Correct Answer: D
Rationale: Antimetabolites interfere with the synthesis of nucleic acids, specifically RNA and DNA. By disrupting one or more stages of RNA and/or DNA synthesis, antimetabolites disrupt the normal cellular processes required for cell division and replication, ultimately leading to inhibition of cell proliferation. This makes them effective agents in targeting rapidly dividing cells, such as cancer cells, which rely heavily on nucleic acid synthesis for their rapid growth. The mechanism of action of antimetabolites is cell cycle-nonspecific, meaning they can affect cells at various stages of the cell cycle rather than being specific to a particular phase like M or S phase.
Question 2 of 5
A client is diagnosed with metastatic adenocarcinoma of the stomach. The physician prescribes mitomycin (Mutamycin) with other chemotherapeutic agents for palliative treatment. How mitomycin does exert its cytotoxic effects?
Correct Answer: A
Rationale: Mitomycin exerts its cytotoxic effects by forming cross-links between adjacent guanine residues in DNA, leading to inhibition of DNA synthesis. This mechanism disrupts the replication of cancer cells, ultimately inducing cell death. Mitomycin is an alkylating agent that primarily targets DNA, making it an effective treatment for certain types of cancers, such as adenocarcinoma of the stomach.
Question 3 of 5
The spouse of a client with gastric cancer expresses concern that the couple's children may develop this type of cancer when they're older. When reviewing risk factors for gastric cancer with the client and family, the nurse explains that a certain blood type increases the risk by 10%. The nurse is referring to:
Correct Answer: A
Rationale: Among the different blood types, individuals with blood type A have been found to have a slightly higher risk of developing gastric cancer. Research has shown that individuals with blood type A are associated with a 10% increased risk of gastric cancer compared to other blood types. This information is important to consider when discussing potential risk factors for gastric cancer with clients and their families.
Question 4 of 5
A client has possible malignancy of the colon, and surgery is scheduled. The rationale for administering Neomycin preoperatively is to:
Correct Answer: C
Rationale: The rationale for administering Neomycin preoperatively in the case of possible malignancy of the colon is to decrease and retard the growth of normal bacteria in the intestines. This is important because surgical procedures involving the colon carry a risk of infection due to the abundant normal bacterial flora present in the intestines. By administering Neomycin prior to surgery, the goal is to reduce the number of bacteria in the colon and minimize the risk of postoperative infections. It is not used to prevent infection or treat cancer directly, nor is it meant to eliminate the need for preoperative enemas.
Question 5 of 5
Which of the ff suggestions should a nurse give breastfeeding mothers to prevent or eliminate mastitis and breast abscess? Choose all that apply
Correct Answer: D
Rationale: Keeping hands and breasts clean is crucial in preventing infections like mastitis and breast abscess. Proper hygiene practices can help reduce the risk of introducing harmful bacteria to the breast during breastfeeding. It is essential for breastfeeding mothers to wash their hands before each feeding session and ensure that the breast is clean before nursing.