Antifibrinolytic drugs:

Correct Answer: A

Rationale: Antifibrinolytic drugs work by inhibiting the activity of plasmin, an enzyme responsible for the breakdown of fibrin clots. By blocking the activation of plasminogen to form plasmin, these drugs help stabilize the formed fibrin clot, thus promoting hemostasis and preventing excessive bleeding. This mechanism is particularly useful in conditions where increased fibrinolysis is a concern, such as in surgical procedures or certain bleeding disorders. Examples of antifibrinolytic drugs include tranexamic acid and aminocaproic acid.

Correct Answer: C

Rationale: Zanamivir is an antiviral medication used to treat influenza, not herpes simplex virus or hepatitis B. Varicella-zoster virus is the cause of chickenpox and shingles, which are treated with other antivirals like acyclovir. This question seems to have an error, as zanamivir is not used for any of the listed conditions.

Correct Answer: A

Rationale: The therapeutic and adverse effects associated with these drugs are related to their adrenergic-receptor-site specificity; that is, the ability to react with specific adrenergic receptor sites without activating them, thus preventing the typical manifestations of sympathetic nervous system (SNS) activation. By occupying the adrenergic receptor site, they prevent norepinephrine released from the nerve terminal or from the adrenal medulla from activating the receptor, thus blocking the SNS effects. The nurse should understand the mechanism of action of adrenergic blocking agents to ensure safe and effective administration.

Correct Answer: D

Rationale: Drowsiness is a common side effect of oxycodone, an opioid analgesic. Patients should be advised to avoid activities requiring alertness, such as driving, while taking this medication. Paresthesia (A), increased intracranial pressure (B), and occipital headache (C) are not typical side effects of oxycodone.

Correct Answer: B

Rationale: Hydroxychloroquine can cause retinal toxicity, leading to vision loss. Regular ophthalmologic examinations are essential to detect early signs of toxicity. While dental, pulmonary, and endocrine health are important, they are not directly related to hydroxychloroquine's side effects. Monitoring for retinal changes is critical to ensure the safe use of this medication.