Antifibrinolytic drugs:

Correct Answer: A

Rationale: Antifibrinolytic drugs work by inhibiting the activity of plasmin, an enzyme responsible for the breakdown of fibrin clots. By blocking the activation of plasminogen to form plasmin, these drugs help stabilize the formed fibrin clot, thus promoting hemostasis and preventing excessive bleeding. This mechanism is particularly useful in conditions where increased fibrinolysis is a concern, such as in surgical procedures or certain bleeding disorders. Examples of antifibrinolytic drugs include tranexamic acid and aminocaproic acid.

Correct Answer: B

Rationale: Dehydration, common in elders from reduced thirst, lowers drug clearance (e.g., renal function drops), risking toxicity-key in pharmacokinetics. Alcohol abuse varies, not primary. Constipation affects excretion less than fluid status. Stomach acid decreases, not increases, with age. Dehydration's impact on volume and clearance drives toxicity risk.

Correct Answer: D

Rationale: Ketamine, an NMDA antagonist, causes dissociative anesthesia. Slurred speech is correct-users often exhibit altered speech, disorientation, and motor impairment. Hypersensitivity to pain contradicts ketamine's analgesia. Loss of consciousness occurs at high doses, but self-injection suggests sub-anesthetic use. Normal gait is unlikely due to ataxia. Tranquil affect (E) doesn't fit agitation or dissociation. Slurred speech reflects ketamine's CNS depression, consistent with abuse scenarios.

Correct Answer: A

Rationale: Insulin glargine is typically administered subcutaneously. Subcutaneous injection allows for slow and continuous absorption of the medication, providing a sustained release of insulin to help regulate blood sugar levels. This route of administration is commonly used for long-acting insulins like insulin glargine to provide basal insulin coverage throughout the day. Sublingual, oral, IV, and other routes are not appropriate for administering insulin glargine.

Correct Answer: D

Rationale: Missing oral contraceptive pills reduces their efficacy, increasing pregnancy risk. If several pills are missed , the hormonal protection is compromised, requiring an alternative method (e.g., condoms) for the cycle's remainder to prevent conception. Immediate pregnancy testing assesses outcome, not prevention. Suggesting a new method addresses future planning, not current risk. Choice C underestimates the risk, as even fewer than three missed pills can disrupt efficacy, depending on timing. The nurse's best instruction (D) ensures immediate protection, aligning with contraceptive guidelines for missed doses, prioritizing safety and efficacy.