ATI RN
microbiology a systems approach test bank Questions
Question 1 of 9
Antibiotics for multiple-resistant microorganisms are:
Correct Answer: D
Rationale: The correct answer is D: Imipenem. Imipenem is a carbapenem antibiotic effective against multiple-resistant microorganisms due to its broad spectrum and resistance to beta-lactamases. It is often used as a last resort for severe infections. Ampicillin (A) and Penicillin (B) are both beta-lactam antibiotics that are less effective against multiple-resistant microorganisms due to widespread resistance mechanisms. Augmentin (C) is a combination of amoxicillin and clavulanic acid, which may have limited efficacy against certain resistant strains but is not as effective as imipenem for treating infections caused by multiple-resistant microorganisms.
Question 2 of 9
The specific prevention (by vaccination) of the disease gas gangrene (caused by Clostridium perfringens) is based on:
Correct Answer: B
Rationale: The correct answer is B: Anatoxin. An anatoxin is a toxin that has been rendered harmless while retaining its ability to stimulate an immune response. Gas gangrene is caused by the toxins produced by Clostridium perfringens, not the bacteria itself. Therefore, vaccination with an anatoxin can trigger the immune system to produce antibodies against the toxin, providing immunity against the disease. A: Killed whole cell vaccine - Gas gangrene is caused by toxins, not the whole bacterium. This type of vaccine may not be effective in preventing the disease. C: There is no specific prevention by vaccination - This is incorrect, as vaccination with an anatoxin can prevent gas gangrene. D: Alive attenuated vaccine - Attenuated vaccines contain live, weakened forms of the pathogen. However, for gas gangrene prevention, targeting the specific toxin with an anatoxin vaccine is more appropriate.
Question 3 of 9
Non - complete phagocytosis is observed during infections with:
Correct Answer: D
Rationale: Rationale: 1. Mycobacterium tuberculosis, Legionella pneumophila, Brucella melitensis can evade complete phagocytosis. 2. Mycobacterium tuberculosis inhibits phagosome-lysosome fusion. 3. Legionella pneumophila can prevent phagosome maturation. 4. Brucella melitensis can survive and replicate within phagocytes. 5. A + B + C together represent non-complete phagocytosis. Summary: - A, B, C individually cause incomplete phagocytosis. - Only when all three are present together (D) is non-complete phagocytosis observed.
Question 4 of 9
Which bacteria is a common cause of urinary tract infections (UTIs)?
Correct Answer: B
Rationale: The correct answer is B: Escherichia coli. E. coli is the most common cause of UTIs due to its ability to colonize the urinary tract. It possesses adhesive factors that enable it to attach to the bladder and cause infection. Clostridium tetani causes tetanus, Mycobacterium leprae causes leprosy, and Bacillus anthracis causes anthrax, none of which are typically associated with UTIs. E. coli's prevalence in the gut and its pathogenic mechanisms make it the leading cause of UTIs.
Question 5 of 9
The branch of pharmacology that addresses drug amounts at various sites in the body after drug administration is called:
Correct Answer: B
Rationale: The correct answer is B: pharmacokinetics. Pharmacokinetics is the study of drug movement in the body, including absorption, distribution, metabolism, and excretion. It focuses on how the body processes a drug over time. Pharmacodynamics (A) is the study of the effects drugs have on the body. Pharmacotherapeutics (C) involves using drugs to treat diseases. Pharmacy (D) is the practice of preparing and dispensing medications. Pharmacokinetics specifically deals with drug concentrations at different body sites after administration, making it the most appropriate choice for this question.
Question 6 of 9
Which structure in bacteria allows them to exchange genetic material during conjugation?
Correct Answer: A
Rationale: Pili in bacteria are responsible for conjugation, allowing the transfer of genetic material between cells. They form a bridge between donor and recipient cells, facilitating the exchange of DNA. Flagella are for movement, capsules for protection, and ribosomes for protein synthesis. Pili is the only structure directly involved in genetic material exchange.
Question 7 of 9
Which of the following microorganisms require a moist environment to survive and most often live in ponds, streams, lakes, and oceans?
Correct Answer: D
Rationale: The correct answer is D: Blastospores. Blastospores are a type of fungal spore that requires a moist environment to survive. They are commonly found in water bodies like ponds, streams, lakes, and oceans. Mycorrhizae (A) are symbiotic associations between fungi and plant roots, not solely dependent on a moist environment. Armillaria gallica (B) is a type of fungus that can survive in various environmental conditions, not specifically reliant on a moist environment. Choice C is a duplicate of Blastospores, making it incorrect.
Question 8 of 9
When doctors of a sanitary and epidemiologic institution examine employees of public catering establishments they often reveal asymptomatic parasitosis, that is when a healthy person is a carrier of cysts that infect other people. What causative agent can parasitize in such a way?
Correct Answer: A
Rationale: The correct answer is A: Dysenteric amoeba. This is because dysenteric amoebas can cause asymptomatic parasitosis, where a healthy person carries cysts that can infect others. Dysenteric amoebas are known to infect the intestines and can be transmitted through contaminated food or water. Choice B, Malarial plasmodium, causes malaria transmitted through mosquitoes. Choice C, Enteral trichomonad, causes diarrhea and is transmitted through contaminated water. Choice D, Dermatotropic leishmania, causes skin lesions and is transmitted through sandfly bites. These choices do not fit the scenario of asymptomatic parasitosis in public catering establishments.
Question 9 of 9
Infections of the CNS can be caused by:
Correct Answer: D
Rationale: The correct answer is D because all three choices, Clostridium botulinum, Morbillivirus morbillorum, and Clostridium tetani, can cause infections of the CNS. Clostridium botulinum can lead to botulism, affecting the nervous system. Morbillivirus morbillorum can cause measles, which can lead to encephalitis. Clostridium tetani can cause tetanus, affecting the central nervous system. Therefore, all three choices can cause infections of the CNS. Choices A, B, and C are incorrect individually because each pathogen can cause CNS infections.