Anti-tetanus gamma globulin is produced by hyperimmunization of donors with tetanus anatoxin. What class of immunoglobulins prevails in this preparation?

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Microbiology Chapter 11 Test Bank Questions

Question 1 of 9

Anti-tetanus gamma globulin is produced by hyperimmunization of donors with tetanus anatoxin. What class of immunoglobulins prevails in this preparation?

Correct Answer: A

Rationale: The correct answer is A: IgG. Anti-tetanus gamma globulin is produced by hyperimmunization, leading to a high concentration of specific antibodies, predominantly IgG. IgG is the most abundant immunoglobulin in the blood and provides long-term immunity against tetanus. IgA is mainly found in mucosal areas, not in gamma globulin preparations. IgM is the first antibody produced in response to an infection and is not the prevailing class in this preparation. IgE is associated with allergic reactions and parasitic infections, not with anti-tetanus immunity.

Question 2 of 9

Which of the following best describes bacterial conjugation?

Correct Answer: A

Rationale: The correct answer is A because bacterial conjugation involves the transfer of genetic material through a sex pilus from a donor bacterium to a recipient bacterium. This process allows for the exchange of genetic material and can lead to increased genetic diversity within bacterial populations. Option B is incorrect because the uptake of free DNA from the environment is known as transformation, not conjugation. Option C is incorrect as transfer of DNA by bacteriophages is called transduction, not conjugation. Option D is incorrect because binary fission is a form of asexual reproduction in bacteria, not a mechanism for genetic exchange.

Question 3 of 9

In which of the following GIT infections, the bacteria adhere to the intestine wall and produce toxins:

Correct Answer: B

Rationale: Rationale: 1. Enteropathogenic E.coli (EPEC) adheres to the intestinal wall using bundle-forming pili. 2. EPEC produces toxins that disrupt cell structure and function, leading to diarrhea. 3. Shigella spp. invade intestinal cells, Salmonella spp. invade and multiply within cells, and Vibrio cholerae produces cholera toxin causing profuse watery diarrhea. Summary: A, C, and D choices are incorrect because they do not specifically adhere to the intestine wall and produce toxins like EPEC does.

Question 4 of 9

What are the two main targets currently used in anti-HIV therapy?

Correct Answer: B

Rationale: The correct answer is B: Reverse transcriptase and protease. Reverse transcriptase converts viral RNA into DNA, a crucial step in viral replication. Protease is responsible for cleaving viral polyproteins into functional proteins. Targeting both enzymes disrupts viral replication. Choice A is incorrect as integrase is not a main target in current therapy. Choice C is incorrect because protease is targeted along with reverse transcriptase, not integrase. Choice D is incorrect as targeting viral glycoproteins is not a main strategy in anti-HIV therapy.

Question 5 of 9

During examination of a 3-month old infant a pediatrician revealed that the baby's oral mucosa and tongue were covered with a thick white deposit. In the material taken from the affected site a bacteriologist revealed the presence of yeast fungi giving the reasons for suspecting a fungal infection which occurs most often in children of this age, namely:

Correct Answer: A

Rationale: The correct answer is A: Candidiasis. In infants, a thick white deposit on the oral mucosa and tongue is indicative of oral thrush, which is caused by the yeast fungus Candida. Infants are particularly susceptible to Candidiasis due to their developing immune systems and use of antibiotics. Favus (B) is a chronic fungal infection of the scalp caused by Trichophyton schoenleinii, typically not seen in infants. Epidermophytosis (C) refers to superficial fungal infections of the skin caused by dermatophytes, not commonly found in the oral cavity of infants. Actinomycosis (D) is a bacterial infection caused by Actinomyces species, not a fungal infection.

Question 6 of 9

A wound infection culture revealed Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-positive. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Staphylococcus aureus. This bacterium is characterized by Gram-positive cocci in clusters, catalase-positive, and coagulase-positive. Staphylococcus aureus is a common pathogen causing wound infections due to its ability to produce toxins and enzymes. Staphylococcus epidermidis (B) is catalase-positive but coagulase-negative, making it less likely to cause infections. Streptococcus pyogenes (C) is catalase-negative and typically causes streptococcal infections, not wound infections. Enterococcus faecalis (D) is catalase-negative and typically associated with urinary tract infections. Thus, Staphylococcus aureus is the most likely causative agent based on the given characteristics.

Question 7 of 9

Which of the following characteristics of mumps infection is NOT true:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Mumps is a contagious disease transmitted through air droplets and direct contact. 2. The correct answer is A because mumps can infect both humans and animals. 3. Choice B is incorrect as mumps is vaccine-preventable. 4. Choice C is correct as mumps is highly contagious. 5. Choice D is accurate as mumps is transmitted via air droplets and direct contact. Summary: The correct answer is A because mumps can infect both humans and animals, making it untrue that only humans can be infected. Choices B, C, and D are incorrect as mumps is vaccine-preventable, highly contagious, and transmitted through air droplets and direct contact.

Question 8 of 9

Specify the microbiological characteristic of the air:

Correct Answer: A

Rationale: The correct answer is A: Contaminated. The air is never completely free of microorganisms, so it is considered contaminated. Microorganisms are ubiquitous in the environment. Permissible limits (B) imply a specific standard, which is not relevant to the general microbiological characteristic of air. Almost pure (C) and pure (D) are not accurate as air always contains some level of microorganisms.

Question 9 of 9

Enzymes used in ELISA are those except:

Correct Answer: A

Rationale: The correct answer is A: Β-lactamase. In ELISA, enzymes like alkaline phosphatase, horseradish peroxidase, and Β-galactosidase are commonly used as labels to detect the presence of specific molecules. Β-lactamase is not typically used in ELISA as it is an enzyme used to hydrolyze β-lactam antibiotics. Therefore, it does not serve the purpose of detecting specific molecules in ELISA. Alkaline phosphatase, horseradish peroxidase, and Β-galactosidase are preferred enzymes in ELISA due to their ability to produce a detectable signal when bound to specific molecules.

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