Ankylosing spondylitis

Questions 60

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Pediatric Immunization NCLEX Questions Quizlet Questions

Question 1 of 5

Ankylosing spondylitis

Correct Answer: A

Rationale: Ankylosing spondylitis is strongly associated with HLA-B27.

Question 2 of 5

Mutations in TAP-1 or TAP-2 may alter the function of the heterodimer TAP. Which of the following is common for patients with TAP mutations?

Correct Answer: C

Rationale: TAP mutations impair MHC Class I antigen presentation, leading to increased susceptibility to upper respiratory infections due to reduced CD8+ T cell responses.

Question 3 of 5

B cell co-receptor phosphorylation sites include Igα/Igβ and which of the following?

Correct Answer: A

Rationale: CD19 contains phosphorylation sites critical for amplifying BCR signaling.

Question 4 of 5

Important role in allergic response; heparin & histamine

Correct Answer: C

Rationale: Basophils release histamine and heparin in allergic responses.

Question 5 of 5

In the adult, the primary lymphoid organs, whose cells expand clonally, are the and secondary lymphoid organs, which create effector cells, are the , as well as mucosa associated lymphoid tissue (MALT) lining the respiratory, GI, and reproductive tracts.

Correct Answer: B

Rationale: Primary lymphoid organs are bone marrow and thymus; secondary are spleen, lymph nodes, and MALT.

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