ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Anaphylaxis can be triggered by cross-linking of IgE receptors on...?
Correct Answer: D
Rationale: Anaphylaxis is triggered by allergen-induced cross-linking of IgE on mast cells, leading to degranulation and histamine release.
Question 2 of 5
Matching: Complement deficiency - Fatal meningococcal infection in males
Correct Answer: D
Rationale: Properdin deficiency, an X-linked condition affecting males, impairs the alternative complement pathway, increasing susceptibility to fatal meningococcal infections. Terminal complement deficiencies (C5-9) also cause neisserial infections but are not sex-linked.
Question 3 of 5
Matching: Immunodeficiency - Lymphopenia plus severe neutropenia
Correct Answer: C
Rationale: Reticular dysgenesis is a severe condition with both lymphopenia and neutropenia due to failure of lymphoid and myeloid precursors.
Question 4 of 5
Which of the following is not a prominent feature of Wiskott-Aldrich syndrome?
Correct Answer: D
Rationale: Wiskott-Aldrich syndrome (WAS) features eczema, thrombocytopenia, and infections, but leukopenia is not typical; lymphocyte counts may be normal or reduced, not a prominent feature.
Question 5 of 5
A 6-month-old presents with recurrent cellulitis and bacteremias due to Staphylococcus aureus. The white blood cell count is 2500 with 5% neutrophils, 10% eosinophils, 35% monocytes, and 50% lymphocytes. The platelet count is 650,000. A brother and a female cousin died at the age of 18 months and 2 years, respectively. The most likely diagnosis is
Correct Answer: C
Rationale: Kostmann disease (severe congenital neutropenia) fits with persistent neutropenia, recurrent Staphylococcus aureus infections, and a family history suggesting autosomal recessive inheritance.