ATI RN
Advanced Pharmacology Test Bank Questions
Question 1 of 5
An overwhelmed nursing student asks the instructor whether there are any tips that will make learning pharmacology easier. The instructor gives an example of the anticoagulant heparin. The instructor indicates that knowing heparin and comparing other drugs to it will facilitate learning the many anticoagulants. Which approach is the instructor using?
Correct Answer: D
Rationale: The prototype approach uses a representative drug like heparin to learn a class (anticoagulants), comparing others to its traits-mechanism, effects, side effects-simplifying study. Mechanism of action is narrower. Generic or trade names focus on nomenclature, not learning strategy. Prototype leverages a familiar example, a proven method for mastering drug groups.
Question 2 of 5
Depression that occurs during cold winter months would be classified as
Correct Answer: C
Rationale: Seasonal Affective Disorder (SAD) is the correct classification for depression that occurs during cold winter months. SAD is a subtype of major depressive disorder characterized by recurrent depressive episodes that occur at a specific time of year, usually in the fall and winter when there is less natural sunlight. This is due to disruptions in circadian rhythms and changes in serotonin and melatonin levels. Symptoms include low energy, oversleeping, weight gain, and feelings of hopelessness. Option A, baby blues, refers to the feelings of sadness, anxiety, and fatigue that many women experience after giving birth. This is a transient condition related to hormonal changes and adjustments to motherhood, not related to seasonal changes. Option B, bipolar disorder, is a mood disorder characterized by periods of depression and mania. While seasonal patterns can sometimes be observed in bipolar disorder, depression occurring only during winter months is more indicative of SAD. Option D, obsessive-compulsive disorder, is an anxiety disorder characterized by intrusive thoughts and repetitive behaviors. It is not typically associated with seasonal patterns of depression. Educationally, understanding the different types of mood disorders and how they present is crucial for healthcare professionals, especially those working in mental health. Recognizing the seasonal pattern of depression can guide appropriate treatment strategies, such as light therapy, lifestyle interventions, and medication management. It is important for students to grasp these distinctions to provide effective care for individuals experiencing mood disorders.
Question 3 of 5
A 48-year-old woman pricks her finger on a rose bush while pruning. A few days later, she develops small, red lesions near the wound and a red track ascending her hand toward her trunk. Her doctor prescribes itraconazole for the sporotrichosis. What is the mechanism of action of this medication?
Correct Answer: C
Rationale: Sporotrichosis, from Sporothrix schenckii, requires antifungals like itraconazole. Option , inhibiting lanosterol to ergosterol conversion, is correct-itraconazole blocks 14-α-demethylase, disrupting fungal membrane synthesis. Option , pore formation, is amphotericin B's mechanism. Option , microtubule disruption, is griseofulvin's. Option , squalene monooxygenase inhibition, is terbinafine's. Option (E), 5-FU conversion, is flucytosine's. Itraconazole's ergosterol inhibition effectively treats this subcutaneous infection, targeting fungal viability.
Question 4 of 5
A local municipality is alerted that low doses of carbon tetrachloride have been dumped into the drinking water. A public health alert is transmitted to all residents of this town. Which of the following signs and symptoms should these residents be aware of?
Correct Answer: C
Rationale: In this scenario, the correct answer is C) Nausea. Nausea is a common symptom of carbon tetrachloride poisoning due to its toxic effects on the liver and kidneys. When carbon tetrachloride is ingested or absorbed into the body, it can lead to liver and kidney damage, causing symptoms such as nausea, vomiting, and abdominal pain. Option A) Convulsions is incorrect because convulsions are not typically associated with carbon tetrachloride poisoning. Carbon tetrachloride poisoning usually manifests with symptoms related to liver and kidney dysfunction rather than neurological symptoms like convulsions. Option B) Eye irritation is also incorrect as carbon tetrachloride exposure is more likely to cause systemic toxic effects rather than isolated eye irritation. While eye irritation can occur with certain chemical exposures, it is not a hallmark symptom of carbon tetrachloride poisoning. Option D) Stupor is not a typical symptom of carbon tetrachloride poisoning. Stupor is a state of near-unconsciousness or insensibility, which is not commonly associated with the toxic effects of carbon tetrachloride on the body. Educationally, it is important for residents to be aware of the signs and symptoms of potential chemical exposures in their environment to take appropriate actions to protect their health. Understanding the specific symptoms of carbon tetrachloride poisoning can help individuals seek timely medical attention and prevent further complications. Awareness of the correct symptoms can also aid healthcare providers in making accurate diagnoses and providing appropriate treatment in cases of poisoning.
Question 5 of 5
A 59-year-old man with a history of depression cuts his wrists in a suicide attempt. He is brought to the local emergency department for care. He has bilateral medial 3-cm lacerations through the skin and subcutaneous tissues that will require sutures. A review of his prior medical history indicates an allergy to 2% lidocaine. The most likely explanation for this is which of the following?
Correct Answer: A
Rationale: In this scenario, the correct answer is A) Allergic. Lidocaine is a local anesthetic commonly used for procedures like suturing. Allergic reactions to lidocaine can occur, presenting as itching, redness, swelling, or in severe cases, anaphylaxis. The patient's history of depression and suicide attempt is not directly related to the lidocaine allergy. Option B) Mast cell mediated is incorrect because while mast cells can be involved in allergic reactions, the primary cause in this case is the patient's allergy to lidocaine, not mast cell activation per se. Option C) Neurogenic is incorrect as it refers to conditions related to nerve dysfunction or injury, not an allergic reaction to lidocaine. Option D) Psychogenic is incorrect as it pertains to psychological factors causing physical symptoms, which is not the case with the lidocaine allergy. Educationally, this question highlights the importance of assessing patients for allergies prior to administering medications and the potential serious consequences of allergic reactions. It also underscores the need for healthcare providers to be vigilant in obtaining thorough medical histories to ensure patient safety during procedures.