An infectious diseases hospital admitted a veterinarian with assumed brucellosis. What serologic test can confirm this diagnosis?

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Microbiology Chapter 10 Test Bank Questions

Question 1 of 5

An infectious diseases hospital admitted a veterinarian with assumed brucellosis. What serologic test can confirm this diagnosis?

Correct Answer: A

Rationale: The correct answer is A: Wright's agglutination reaction. For brucellosis diagnosis, this test detects antibodies against Brucella species. Wright's test specifically targets agglutinins, which are produced in response to Brucella infection. The other choices are incorrect because: B: Widal's test is used for typhoid fever caused by Salmonella typhi. C: Ascoli's test is for pneumococcal infections. D: Weigl's test is used for typhus fever caused by Rickettsia prowazekii.

Question 2 of 5

A patient has been hospitalized with provisional diagnosis of botulism. What serological reaction should be used to reveal botulinum toxin?

Correct Answer: A

Rationale: The correct answer is A: Neutralization reaction. This is the most appropriate serological test to reveal botulinum toxin because it involves mixing the patient's serum with known botulinum antitoxin. If the patient's serum contains botulinum toxin, it will neutralize the antitoxin, leading to a lack of toxin-neutralizing ability. The other choices are incorrect because agglutination reaction involves clumping of cells, not suitable for detecting botulinum toxin; Bordet-Gengou test is used to detect antibodies in pertussis infection, not botulinum toxin; and precipitation reaction involves the formation of a solid when two solutions are mixed, not ideal for detecting botulinum toxin.

Question 3 of 5

A patient has severe catarrhal symptoms. Material growth on Bordet-Gengou agar showed mercury- drop like colonies. Examination of the blood smears revealed some small ovoid gram-negative bacilli sized 1-3 microns. What microorganisms were isolated?

Correct Answer: A

Rationale: The correct answer is A: Bordetella. The presence of mercury-drop like colonies on Bordet-Gengou agar indicates Bordetella pertussis. The small ovoid gram-negative bacilli sized 1-3 microns are characteristic of Bordetella species. Catarrhal symptoms are typical of pertussis caused by Bordetella pertussis. Summary of other choices: B: Corynebacteria do not typically exhibit mercury-drop like colonies or small ovoid shapes. C: Mycobacteria are acid-fast bacilli and do not grow on Bordet-Gengou agar. D: Meningococcus is a gram-negative diplococcus and does not match the description provided.

Question 4 of 5

A man was admitted to the hospital on the 5th day of disease that manifested itself by jaundice, muscle aching, chill, nose bleedings. In course of laboratory diagnostics a bacteriologist performed darkfield microscopy of the patient's blood drop. Name a causative agent of this disease:

Correct Answer: A

Rationale: The correct answer is A: Leptospira interrogans. Darkfield microscopy is used to visualize spirochetes, which are spiral-shaped bacteria. Leptospira is a spirochete bacterium that causes leptospirosis, which presents with jaundice, muscle aching, chill, and nosebleeds. Leptospira is commonly transmitted through contact with contaminated water or soil. B: Borrelia dutlonii causes Lyme disease, which is transmitted by ticks and does not typically present with jaundice or nosebleeds. C: Calymmatobacterium granulomatis causes granuloma inguinale, a sexually transmitted infection that does not present with the symptoms described. D: Bartonella bacilloformis causes Carrion's disease, which presents with fever, anemia, and skin lesions but not jaundice or nosebleeds.

Question 5 of 5

A 30 y.o. patient is diagnosed with amebic dysentery. This diagnosis was bacteriologically confirmed. Name the preparation for its treatment:

Correct Answer: A

Rationale: The correct answer is A: Metronidazole. Amebic dysentery is caused by the parasite Entamoeba histolytica, not bacteria. Metronidazole is the drug of choice for treating this parasitic infection. It works by disrupting the DNA structure of the parasite, leading to its death. Mebendazole (B) is used to treat certain worm infections, not amebic dysentery. Itrakonazole (C) is an antifungal medication and not effective against parasites. Furacillin (D) is an antibacterial agent and not suitable for treating parasitic infections like amebic dysentery.

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