ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
An article published in the Oncoimmunology journal in September 2018. It is discussing an immunotherapy approach that relies on designing and infecting the cancer patient two viruses expressing Melanoma-associated antigen A3 (MAGE-A3). The two viruses, a replication-deficient type-5 human adenoviral (Ad-MAGEA3) and Maraba MGI rhabdovirus(MGI-MAGEA3), are studied in this article preclinically by infecting nonhuman primates(monkeys). This immunotherapy approach is considered:
Correct Answer: A
Rationale: Using viruses to express tumor antigens like MAGE-A3 to stimulate an immune response classifies this as a vaccination strategy in cancer immunotherapy.
Question 2 of 5
Matching: Immunodeficiency - Elevated IgE levels and eosinophilia
Correct Answer: D
Rationale: Hyper-IgE syndrome is defined by elevated IgE and eosinophilia, alongside recurrent infections and skin findings.
Question 3 of 5
In addition to recurrent staphylococcal abscesses and elevated serum IgE, the clinical manifestations of hyperimmunoglobulinemia E (hyper-IgE) syndrome frequently include which of the following?
Correct Answer: B
Rationale: Hyper-IgE syndrome commonly includes pneumatoceles (lung cysts) from recurrent pneumonias, alongside staphylococcal abscesses and high IgE.
Question 4 of 5
Long-term treatment of the disease described in Question 27 is best accomplished with
Correct Answer: D
Rationale: Granulocyte colony-stimulating factor (G-CSF) is the mainstay long-term treatment for Kostmann disease, boosting neutrophil production.
Question 5 of 5
An 8-year-old child having coarse facial features seen by dentist because of failure to shed primary teeth and visited an orthopedician due to frequent fractures of lower limbs, now presented with skin abscesses and eczema. Of the following, the MOST likely diagnosis is
Correct Answer: D
Rationale: Hyper-IgE syndrome features coarse facies, retained primary teeth, recurrent fractures, skin abscesses, and eczema due to STAT3 mutations.