An 80-year-old man is admitted to the hospital after falling on an icy sidewalk and fracturing his hip. He undergoes open reduction and internal fixation of the fracture. At surgery, there does not appear to be any bone disease at the fracture site. The patient was previously asymptomatic. Physical examination findings are otherwise unremarkable. Serum protein electrophoresis and immunofixation show an IgM κ monoclonal protein (0.3 g/dL). The complete blood cell count and serum creatinine levels are normal. Skeletal survey shows no additional bone defects. Which of the following statements is true for this patient?

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Hematology Oncology Question Bank Questions

Question 1 of 5

An 80-year-old man is admitted to the hospital after falling on an icy sidewalk and fracturing his hip. He undergoes open reduction and internal fixation of the fracture. At surgery, there does not appear to be any bone disease at the fracture site. The patient was previously asymptomatic. Physical examination findings are otherwise unremarkable. Serum protein electrophoresis and immunofixation show an IgM κ monoclonal protein (0.3 g/dL). The complete blood cell count and serum creatinine levels are normal. Skeletal survey shows no additional bone defects. Which of the following statements is true for this patient?

Correct Answer: D

Rationale: Monoclonal gammopathy of undetermined significance (MGUS) is indicated by low IgM (0.3 g/dL), normal CBC, creatinine, and no bone lesions. Regular follow-up is needed (1% annual progression risk). Myeloma (A) requires end-organ damage. IgM has higher risk than IgG (B incorrect). Bone scan (C) is unnecessary; risk is 1%, not 10% (E).

Question 2 of 5

A 5-day-old full-term male presents with intense cyanosis, tachypnea, and tachycardia. Physical examination reveals cyanosis of the skin and mucous membranes; the lungs, heart, pulses, and general examination show no abnormalities. Arterial blood gas determination reveals a PaOâ‚‚ of 95 while the patient is breathing room air and an oxygen saturation of 40%. The most likely diagnosis is

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Matching: Hemolytic anemia - Microcytosis

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Matching: Anemia - Copper deficiency

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Matching: Anemia - Leukemia

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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