ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
An 8-year-old boy presents to the clinic with an extremely itchy rash for the past 2 days. He is the fourth student from his class to present with the same symptoms. The rash is across his hands, wrists, and elbows bilaterally. Small erythematous papules with obvious burrows, which look like insect bites, are aligned in 8-cm segments. What is the most appropriate treatment?
Correct Answer: D
Rationale: Permethrin is the first-line treatment for scabies (Sarcoptes scabiei), killing mites and eggs, addressing the itchy rash with burrows seen in outbreaks.
Question 2 of 5
A 17-year-old high school football player presents to clinic with painful burning of his feet. Football practice started 3 weeks ago, and for the past week, he has had blisters and cracking of the skin of his feet. The skin between his toes is erythematous and scaly. He is diagnosed with tinea pedis and started on clotrimazole. What is the mechanism of action of clotrimazole?
Correct Answer: D
Rationale: Clotrimazole inhibits ergosterol synthesis by blocking 14-α-demethylase, weakening fungal membranes in tinea pedis (athlete’s foot).
Question 3 of 5
Third generation cephalosporins has the following characteristic EXCEPT:
Correct Answer: C
Rationale: Not all third-generation cephalosporins (e.g., ceftriaxone) can be used orally; many are parenteral only, making C the exception.
Question 4 of 5
Which of the following is an advantage of benzyl penicillin use:
Correct Answer: A
Rationale: Benzyl penicillin’s water solubility allows IV use in emergencies, which is an advantage over its short duration, acid instability, and narrow spectrum.
Question 5 of 5
Alkalinization of urine is performed with sulphonamides to reduce crystalluria
Correct Answer: B
Rationale: Alkalinization increases sulphonamide solubility in urine, reducing crystalluria, making this statement correct.