An 18-year-old man is brought to the emergency department by a friend after smoking crack cocaine because he was 'acting funny.' His temperature is 38°C (100.4°F), pulse is 110 beats/minute, and he appears agitated. Which of the following is an effect of cocaine intoxication?

Correct Answer: D

Rationale: Cocaine intoxication (agitation, tachycardia, fever) causes vasoconstriction , via sympathetic stimulation, raising BP and temperature. Hypercoagulability occurs but isn't primary. Hypocoagulability and hypothermia oppose effects. Vasodilation (E) is wrong. This drives his symptoms.

Correct Answer: C

Rationale: Estrogen suppresses androgen production , starving androgen-dependent prostate cancer. Choice A misstates cell death. Choice B overstates testosterone elimination. Choice D misattributes nutrient blockade. C explains the hormonal mechanism accurately, making it the best response.

Correct Answer: D

Rationale: Metformin is a medication commonly used to treat type 2 diabetes by helping to control high blood sugar levels. It works by decreasing the amount of sugar produced by the liver and increasing the body's response to insulin. By aiding in controlling blood glucose levels, metformin helps prevent complications of diabetes such as kidney damage, blindness, nerve problems, and loss of limbs. It does not lower blood pressure, diminish seizure activity, increase heart rate, or decrease gastrointestinal secretions.

Correct Answer: B

Rationale: Diphenhydramine's frequent use risks dizziness , an anticholinergic effect. Appetite enhancement isn't typical. Hypotension and bradycardia are less common. Urinary retention (E) occurs but isn't listed. Dizziness reflects CNS depression from high dosing.

Correct Answer: D

Rationale: All these drugs require metabolic activation to exert their therapeutic effects, making them prodrugs.

Correct Answer: A

Rationale: Therapeutic classification groups drugs by disease or condition treated (e.g., antihypertensives for hypertension), focusing on clinical use. Mechanism of action (e.g., beta-blockers) targets how drugs work. Chemical classification uses structure. Pharmacological overlaps but emphasizes action. Therapeutic fits, reflecting treatment purpose, a practical nursing framework.

Correct Answer: B

Rationale: Hydroxychloroquine can cause retinal toxicity, leading to vision loss. Regular ophthalmologic examinations are essential to detect early signs of toxicity. While dental, pulmonary, and endocrine health are important, they are not directly related to hydroxychloroquine's side effects. Monitoring for retinal changes is critical to ensure the safe use of this medication.

Correct Answer: C

Rationale: Zanamivir is an antiviral medication used to treat influenza, not herpes simplex virus or hepatitis B. Varicella-zoster virus is the cause of chickenpox and shingles, which are treated with other antivirals like acyclovir. This question seems to have an error, as zanamivir is not used for any of the listed conditions.

Correct Answer: D

Rationale: When teaching patients about taking beta2-blocking drugs for the treatment of angina, it is important to include information about monitoring for signs of heart failure. Weight gain can be an early sign of fluid retention, which can indicate heart failure. Instructing patients to alert their healthcare provider if they experience a weight gain of 2 lb or more in 24 hours or 5 lb or more in 1 week can help in early detection and management of potential heart failure. This is crucial for the safety and well-being of the patient.