Aminoglycosides have the following unwanted effects:

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Drugs Affecting the Cardiovascular and Renal Systems Edapt Quizlet Questions

Question 1 of 5

Aminoglycosides have the following unwanted effects:

Correct Answer: C

Rationale: The correct answer is C because aminoglycosides are known to cause ototoxicity and nephrotoxicity as unwanted effects. Ototoxicity refers to damage to the inner ear structures, leading to hearing loss or imbalance, while nephrotoxicity refers to kidney damage. Pancytopenia (choice A) is not typically associated with aminoglycosides. Hepatotoxicity (choice B) is not a common side effect of aminoglycosides. Irritation of gastrointestinal mucosa (choice D) is also not a known adverse effect of aminoglycosides.

Question 2 of 5

Tick the antiviral drug which belongs to endogenous proteins:

Correct Answer: C

Rationale: Interferon alfa is the correct answer as it is an endogenous protein produced by the immune system in response to viral infections. It helps to inhibit viral replication and spread. Amantadine is a synthetic antiviral drug that works by blocking viral replication. Saquinavir is a protease inhibitor used to treat HIV. Pencyclovir is an antiviral drug used to treat herpes infections. Therefore, choices A, B, and D are incorrect as they are synthetic antiviral drugs, while choice C is correct as it is an endogenous protein with antiviral properties.

Question 3 of 5

Which of the following pairs of drugs would be appropriate for a patient with hypertrophic cardiomyopathy?

Correct Answer: A

Rationale: The correct answer is A: Isosorbide mononitrate and nifedipine. Isosorbide mononitrate is a vasodilator that reduces the workload on the heart, beneficial for hypertrophic cardiomyopathy. Nifedipine is a calcium channel blocker that helps relax the heart muscle. Nitroglycerin (B and C) and captopril (B) are not commonly used in hypertrophic cardiomyopathy. Verapamil (C) can worsen symptoms in some patients with hypertrophic cardiomyopathy. Metoprolol (D) is a beta-blocker that may be used in some cases but is not as effective as nifedipine for this condition.

Question 4 of 5

Which of the following antiarrhythmic drugs would be absolutely contraindicated for this patient?

Correct Answer: C

Rationale: The correct answer is C: Quinidine. Quinidine is contraindicated due to its potential to prolong the QT interval, leading to serious arrhythmias like Torsades de Pointes. Mexiletine and Lidocaine are sodium channel blockers with lower risk of QT prolongation. Phenytoin is an anti-seizure drug and does not typically impact cardiac conduction. Therefore, Quinidine is the absolute contraindication for this patient.

Question 5 of 5

In patients with chronic granulomatous disease which of the following agents increases the synthesis of tumor necrosis factor, leading to activation of phagocytosis?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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