All the following are secondary causes of hypercholesterolemia EXCEPT

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Pediatric Endocrine System Questions

Question 1 of 5

All the following are secondary causes of hypercholesterolemia EXCEPT

Correct Answer: D

Rationale: Obesity (A), cholestasis (B), hypothyroidism (C), and nephrotic syndrome (E) raise cholesterol. Anorexia nervosa (D) typically lowers it due to malnutrition.

Question 2 of 5

The MOST common presentation of mitochondrial β-oxidation of fatty acids disorders is

Correct Answer: D

Rationale: Fatty acid oxidation disorders (e.g., MCAD) most commonly present with hypoglycemic coma from fasting stress, more frequent than cardiomyopathy (A), weakness (B), tubulopathy (C), or rhabdomyolysis (E).

Question 3 of 5

A 16-year-old male has a tall stature but no facial, axillary, or pubic hair. His penis and scrotum are obscured by pubic adipose tissue, but they appear infantile. Chromosome analysis reveals XY karyotype. His serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels are elevated. The most likely diagnosis is

Correct Answer: B

Rationale: Elevated FSH/LH with underdeveloped gonads and XY karyotype indicate primary hypogonadism (e.g., Klinefelter-like, though not specified as XXY here).

Question 4 of 5

Diabetes insipidus is associated with all of the following EXCEPT

Correct Answer: C

Rationale: Diabetes mellitus (glucose-related) is unrelated to diabetes insipidus (water balance disorder); others affect the hypothalamic-pituitary axis.

Question 5 of 5

Hall Pallister syndrome includes all of the following EXCEPT

Correct Answer: D

Rationale: Maternal DES exposure is not linked to Hall-Pallister syndrome, a genetic condition with pituitary and limb anomalies.

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