ATI RN
openstax microbiology test bank Questions
Question 1 of 9
All statements of viral neutralization reaction are true except:
Correct Answer: A
Rationale: Rationale: A: Incorrect - The complement system is not directly involved in the viral neutralization reaction. B: Correct - Specific antibodies neutralize viruses by blocking their ability to infect cells. C: Incorrect - Antibodies are titrated, but only one serum sample is required for neutralization testing. D: Incorrect - Viral neutralization is primarily used to measure antibody response, not to identify newly isolated viruses.
Question 2 of 9
Viruses can infect
Correct Answer: D
Rationale: The correct answer is D because viruses have the ability to infect all organisms, including plants, bacteria, animals, and even fungi. Viruses are non-living entities that require a host cell to replicate and spread. They can infect a wide range of organisms by attaching to specific receptors on the host cell's surface. Therefore, the correct answer is D as viruses have the capability to infect all living organisms. Choices A, B, and C are incorrect because viruses can infect not only plants, bacteria, and animals but also other organisms, making choice D the most comprehensive and accurate option.
Question 3 of 9
Which is NOT a property of interferon?
Correct Answer: D
Rationale: Interferon is a cell-specific protein that is produced and released from infected cells in response to viral infections. It acts extracellularly to interfere with viral replication, not to inactivate the virus itself. Interferon is not coded for by cellular DNA, but by viral RNA during infection. Therefore, the correct answer, D, is that interferon is not virus-specific but is cell-specific. This is because interferon can be produced by various cell types in response to different types of viral infections, making it a broad-spectrum antiviral defense mechanism.
Question 4 of 9
The Ziehl-Neelsen stain is used to detect:
Correct Answer: B
Rationale: The Ziehl-Neelsen stain is specifically designed to detect acid-fast bacteria like Mycobacterium tuberculosis. It utilizes a carbol fuchsin dye that binds to the high lipid content in the cell wall of acid-fast bacteria, making them appear red under a microscope. This staining method is crucial for the diagnosis of tuberculosis and leprosy. Gram-positive bacteria (Choice A) are not detected by this stain since they have a different cell wall structure. Capsulated bacteria (Choice C) and fungal spores (Choice D) also have distinct characteristics that are not targeted by the Ziehl-Neelsen stain.
Question 5 of 9
Which of the following drugs is not used to treat influenza?
Correct Answer: A
Rationale: Acyclovir is the correct answer because it is an antiviral drug used to treat herpes simplex and varicella-zoster viruses, not influenza. Tamiflu, Amantadine, and Relenza are used to treat influenza by inhibiting viral replication or easing symptoms. Acyclovir's mechanism of action targets different viruses, making it ineffective for treating influenza.
Question 6 of 9
Which of the following(s) is/are the determinants of antigenicity?
Correct Answer: D
Rationale: The correct answer is D, as all options A, B, and C are determinants of antigenicity. A: Chemical nature influences how the immune system recognizes antigens. B: The size of the antigen affects its ability to be recognized by immune cells. C: Antigens of foreign origin are more likely to trigger an immune response. Therefore, all of these factors together play a crucial role in determining antigenicity.
Question 7 of 9
Which of the following is an active transport mechanism?
Correct Answer: D
Rationale: The correct answer is D: pinocytosis. This is an active transport mechanism where cells engulf fluids or solutes through vesicles. Energy is required to transport substances against a concentration gradient. A is incorrect as pinocytosis is an active process, not passive like pinocytosis. B is incorrect as facilitated diffusion is a passive process that uses carrier proteins to move substances down a concentration gradient. C is incorrect as filtration is a passive process that relies on pressure gradients to move substances across a barrier. Therefore, D is the correct choice as it involves the active transport of substances into the cell.
Question 8 of 9
Which one is FALSE:
Correct Answer: B
Rationale: The correct answer is B because collecting specimens from the surface of a wound does not provide adequate samples for anaerobic agent detection. Anaerobic agents thrive in deep tissue environments with low oxygen levels, making surface specimens unreliable. Tissue samples and aspirations (choice A) are superior for diagnosing skin infections. Excessive production of toxins, not skin rash (choice C), causes symptoms in some infections. While healthy skin provides some protection, it is not completely impenetrable to microorganisms (choice D).
Question 9 of 9
During fibergastroscopy a patient with ulcer disease of the stomach, the mucosal biopsy is taken from the area of an ulcer. Impression smear is prepared from biopsy material and stained by Gram method; the rest of biopsy material is tested for urease activity. Microscopy of the impression smear revealed gram- negative spiral-shaped microorganisms, urease activity test is positive. What bacteria were detected?
Correct Answer: A
Rationale: The correct answer is A: Helicobacter pylori. Rationale: 1. Gram-negative spiral-shaped microorganisms match the morphology of Helicobacter pylori. 2. Positive urease activity is a characteristic feature of Helicjsonacter pylori. 3. Helicobacter pylori is specifically associated with gastric ulcers and is a common pathogen in the gastrointestinal tract. Summary: Choice B, Campilobacter jejuni, is a gram-negative curved bacterium but is not typically associated with gastric ulcers or urease activity. Choice C, Treponema pallidum, is a spirochete bacterium causing syphilis, which is not related to gastric ulcers. Choice D, Spirilla minor, is a generic term for spiral-shaped bacteria and is not a specific pathogen associated with gastric ulcers or urease activity.