All of the following statements regarding verapamil are true EXCEPT:

Correct Answer: B

Rationale: Verapamil is a calcium channel blocker that decreases heart rate by blocking L-type calcium channels in the heart. Choice B, stating it increases heart rate, is incorrect. Verapamil relaxes coronary artery smooth muscle (Choice C) and depresses cardiac contractility (Choice D), making them true statements. So, the correct answer is B as it contradicts the pharmacological effects of verapamil.

Correct Answer: A

Rationale: The correct answer is A: TRUE. The hypothalamus secretes thyrotropin-releasing hormone (TRH) which stimulates the anterior pituitary to release thyroid-stimulating hormone (TSH), which in turn stimulates the thyroid gland to produce thyroid hormones. This demonstrates the hypothalamic control over the thyroid gland. Choices B, C, and D are incorrect because the hypothalamus does indeed play a crucial role in regulating the thyroid gland, making the statement true rather than false, all-encompassing, or none at all.

Correct Answer: D

Rationale: The correct answer is D, "All of the above." Insulin therapy can lead to hypoglycemia due to excessive insulin dosage, insulin allergy in some rare cases, and lipodystrophy at injection sites from repeated injections. Each complication is a potential risk of insulin therapy, making all choices relevant. Therefore, option D is the correct answer as it encompasses all possible complications. Choices A, B, and C individually address specific complications but do not cover the full scope of potential issues associated with insulin therapy, making them incorrect in this context.

Correct Answer: C

Rationale: Rationale: C: Aspirin inhibits phospholipase A2. This statement is FALSE. Aspirin does not directly inhibit phospholipase A2. The correct answer is C. Summary: A: TRUE - Aspirin irreversibly inhibits COX. B: TRUE - Aspirin interferes with the chemical mediators of the kallikrein system. D: TRUE - Aspirin inhibits thromboxane A2 formation.

Correct Answer: C

Rationale: The correct answer is C: Inhibits calcineurin. Sirolimus inhibits the mTOR pathway by binding to FKBP12 and forming a complex that inhibits the activity of mTOR complex 1. Calcineurin is not directly involved in the mechanism of action of sirolimus. Choice A is incorrect because sirolimus does not involve anti-idiotype antibodies. Choice B is incorrect because sirolimus does not modulate the CD3 receptor. Choice D is incorrect because sirolimus does not mediate ADCC towards T lymphocytes.