ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
All of the following drugs demonstrate a fungicidal effect, EXCEPT:
Correct Answer: D
Rationale: Terbinafine, amphotericin B, and ketoconazole are fungicidal, killing fungi. Miconazole is typically fungistatic, inhibiting growth rather than killing, though it can be fungicidal at high doses.
Question 2 of 5
The drug, inhibiting uncoating of the viral RNA:
Correct Answer: B
Rationale: Rimantadine inhibits the M2 ion channel of influenza A, preventing uncoating of viral RNA, thus blocking viral replication.
Question 3 of 5
The drug used for influenza A prevention is:
Correct Answer: B
Rationale: Rimantadine prevents influenza A by inhibiting the M2 ion channel, blocking viral uncoating, making it effective for prophylaxis.
Question 4 of 5
Stimulation of H-receptors can produce the following effects, choose the false one:
Correct Answer: C
Rationale: Histamine H1 receptor stimulation causes bronchoconstriction (not dilatation), vasodilation of small vessels, and sensory nerve irritation. H2 receptors mediate gastric secretion.
Question 5 of 5
Fexofenadine is a metabolite of:
Correct Answer: D
Rationale: Fexofenadine is an active metabolite of terfenadine, a second-generation antihistamine, designed to reduce cardiac side effects like arrhythmias.