All of the following can be a consequence of the formation of NETS with the exception of:

Correct Answer: A

Rationale: The correct answer is A because NETs (Neutrophil Extracellular Traps) are released by neutrophils to trap and kill microbes extracellularly. Step 1: NETs are composed of DNA, histones, and antimicrobial proteins. Step 2: They trap microbes at the site of infection. Step 3: The antimicrobial proteins in NETs kill the trapped microbes. Step 4: Neutrophils themselves do not contain microbes inside phagolysosomes, so the killing of microbes contained in phagolysosomes is not a direct consequence of NET formation. Therefore, choice A is the exception. Choices B, C, and D are incorrect as they are all consequences of NET formation.

Correct Answer: A

Rationale: The correct answer is A. Naïve lymphocytes require activation through recognition of specific antigen, costimulatory signaling, and cytokines. Migration into an inflammatory site is not a requirement for full activation. Naïve lymphocytes can be activated in secondary lymphoid organs where antigen presentation occurs. Migration to inflammatory sites occurs after activation to fight infections.

Correct Answer: D

Rationale: The correct answer is D because current guidelines actually recommend early introduction of peanuts to prevent peanut allergies, not complete avoidance. This is based on research showing early introduction can reduce the risk of developing peanut allergies. Choice A is correct as sensitization is a key step in allergic reactions. Choice B is correct as inhaled allergens can cause hay fever. Choice C is correct as food allergies can indeed manifest as hives.

Correct Answer: A

Rationale: Rationale: Option A is correct because genetic factors have been identified as playing a role in predisposition to develop MS. Studies have shown a higher risk among individuals with family history. Option B is incorrect because environmental factors, such as vitamin D levels and viral infections, are known to influence MS development. Option C is incorrect as MS is more prevalent in North America and Europe. Option D is incorrect because MS is primarily mediated by T-cell responses, not autoantibodies.

Correct Answer: C

Rationale: Rationale: 1. Class switching in B cells involves changing the class of antibody produced. 2. This allows the B cell to stop making one class of antibody and start making another. 3. This process enhances the immune response by generating antibodies with different functions. 4. Differentiating into a memory cell (choice A) is a separate process from class switching. 5. Making two or more antibody classes simultaneously (choice B) is not a characteristic of class switching. 6. Costimulatory signals from T helper cells (choice D) are important for B cell activation but not directly related to class switching.