All of the following are symptoms of endocarditis except:

Correct Answer: C

Rationale: The correct answer is C: leg swelling. Endocarditis is an infection of the inner lining of the heart chambers and valves. Symptoms typically include fever, chills, weight loss, and muscle aches due to the body's immune response to the infection. Leg swelling is not a common symptom of endocarditis. It may occur in conditions like heart failure but is not directly associated with endocarditis. Therefore, choice C is the correct answer. Choices A, B, and D are incorrect because fever and chills, weight loss, and muscle aches are commonly seen in endocarditis due to the systemic inflammatory response to the infection.

Correct Answer: A

Rationale: The most likely diagnosis is Actinomycosis. This is because the patient's presentation of a painful swelling with a fistula containing white granules and yellow-green honeycomb-like tissue is classic for Actinomycosis. Actinomyces is a gram-positive anaerobic bacterium that forms sulfur granules in tissues. Tuberculosis (B) typically presents with caseating granulomas, not sulfur granules. Leprosy (C) presents with skin lesions and nerve damage, not characteristic of this case. Syphilis (D) usually presents with painless ulcers and rash, not the painful swelling and fistula seen in this patient.

Correct Answer: B

Rationale: The correct answer is B (Urethra). Resident microflora are typically found in various parts of the body where they establish a stable population without causing harm. The urethra is one of the locations where resident microflora are commonly present, helping to maintain a healthy microbial balance and prevent pathogenic bacteria from colonizing the area. In contrast, choices A, C, and D are not typical locations for resident microflora. Blood is normally sterile, the lungs have a different microbial environment due to their exposure to the external environment, and the cerebro-spinal fluid is also typically sterile to prevent infections in the central nervous system.

Correct Answer: C

Rationale: Neonatal meningitis is commonly caused by E. coli K1 and group B streptococci due to their ability to cross the blood-brain barrier in newborns. E. coli K1 is a frequent cause in early-onset cases, while group B streptococci are common in late-onset cases. Neisseria meningitidis and streptococcus agalactiae are not as likely to cause neonatal meningitis. Listeria and shigella are also uncommon causes in neonates. Therefore, choice C is the most likely pair of organisms responsible for neonatal meningitis.

Correct Answer: B

Rationale: The correct answer is B: Bacillus subtilis. Bacillus subtilis is known for its ability to resist heat and radiation due to its formation of endospores, which are highly resistant structures that protect the bacterium from harsh environmental conditions. This resilience allows Bacillus subtilis to survive in extreme environments where other bacteria cannot. Explanation of other choices: A: Escherichia coli is not known for its exceptional resistance to heat and radiation. C: Pseudomonas aeruginosa is not particularly resistant to heat and radiation compared to Bacillus subtilis. D: Clostridium perfringens is not as well-known for its heat and radiation resistance as Bacillus subtilis.

Correct Answer: A

Rationale: The correct answer is A: Acid resistance. Tuberculosis mycobacteria have a unique cell wall structure that makes them resistant to acid-fast staining methods like Ziehl-Neelsen. This is due to the high lipid content of their cell walls, specifically mycolic acids, which prevent the penetration of stains and acids. The red bacilli observed in the smear indicate that the mycobacteria retained the primary stain (carbolfuchsin) after acid-alcohol decolorization, confirming their acid resistance. Summary: - Choice A: Acid resistance is correct due to the unique cell wall structure of tuberculosis mycobacteria. - Choice B: Alkali resistance is incorrect as mycobacteria are not known for being resistant to alkalis. - Choice C: Alcohol resistance is incorrect as mycobacteria are not specifically resistant to alcohols. - Choice D: Encapsulation is incorrect as mycobacteria are not encapsulated bacteria.

Correct Answer: B

Rationale: The correct answer is B because a supercapsid is a lipoprotein membrane that encloses the nucleocapsid, providing protection to the genetic material inside. This structure is distinct from the capsid which is the protein coat surrounding the nucleic acid. Choice A is incorrect as there is no shell located between the capsid and supercapsid. Choice C is incorrect as it describes the nucleocapsid itself, not the supercapsid. Choice D is incorrect as a protein envelope around the nucleic acid does not specifically refer to a supercapsid.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Salmonella enterica, Clostridium botulinum, and Escherichia coli are all bacteria known to cause food poisoning. Salmonella causes symptoms like diarrhea and vomiting; Clostridium botulinum produces a toxin leading to paralysis; Escherichia coli can cause severe stomach cramps and bloody diarrhea. Therefore, selecting "All of the above" is correct because all three bacteria are commonly associated with foodborne illnesses. Choices A, B, and C on their own are incorrect as they each represent only one bacterium known to cause food poisoning, whereas the correct answer encompasses all three.

Correct Answer: A

Rationale: The correct answer is A: protein envelope around the nucleic acid. Viral capsid is the protein coat that surrounds and protects the viral nucleic acid (DNA or RNA). This structure helps in protecting the genetic material from degradation and facilitates the attachment of the virus to host cells. Option B is incorrect as it suggests the nucleic acid is coated with protein, which is not the case. Option C is incorrect as not all viruses have an outer membrane. Option D is incorrect as viruses typically do not have a lipoprotein membrane.