ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
All of the following are associated with chronic granulomatous disease (CGD) EXCEPT
Correct Answer: B
Rationale: Chronic granulomatous disease (CGD) is an X-linked or autosomal recessive disorder characterized by defective phagocyte respiratory burst, leading to recurrent infections (e.g., Aspergillus pneumonia, perianal abscess) with catalase-positive organisms. Pyloric outlet obstruction is not a feature of CGD; it is more associated with gastrointestinal conditions unrelated to immunodeficiency.
Question 2 of 5
A 40-day-old, previously healthy, fullterm female infant manifests fever, lethargy, and poor feeding for 12 hours. Physical examination reveals a lethargic child with vital signs of RR 70, HR 185, BP mean 25, T 39.50°C. The peripheral perfusion is poor, the chest reveals retractions, the abdomen is soft and reveals persistence of the umbilical cord, and the extremities are cool. Laboratory studies reveal a white blood cell count of 65,000 and a platelet count of 105,000. Family history reveals that a male sibling died suddenly at the age of 2 months, 10 years prior to the birth of this child. The most likely diagnosis is
Correct Answer: D
Rationale: Leukocyte adhesion deficiency (LAD) presents with delayed umbilical cord separation, recurrent infections, and leukocytosis (WBC 65,000) due to impaired neutrophil migration. The family history suggests an autosomal recessive condition like LAD.
Question 3 of 5
Which of the following is not true of monocytes and neutrophils?
Correct Answer: A
Rationale: Monocytes do not have unlimited division capacity; they differentiate into macrophages with limited proliferation, making A untrue.
Question 4 of 5
Reported complications of intravenous immunoglobulin therapy include all of the following EXCEPT
Correct Answer: D
Rationale: AIDS is not a reported complication of IVIG; hepatitis C was historically linked to contaminated batches, but modern IVIG is screened and safe.
Question 5 of 5
Neutropenia (for white children 1 year of age or older) is defined as an absolute neutrophil count (ANC) less than
Correct Answer: C
Rationale: Neutropenia in children over 1 year is defined as ANC < 1500/mm3, indicating reduced neutrophil levels increasing infection risk.