ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
Alendronate
Correct Answer: A
Rationale: Alendronate (bisphosphonate) causes esophagitis and can impair renal function if not cleared properly.
Question 2 of 5
The following statement is correct regarding ADH antagonists:
Correct Answer: D
Rationale: ADH antagonists (e.g., tolvaptan, conivaptan) treat SIADH by increasing water excretion, risking hyponatremia. Tolvaptan is V2-selective, conivaptan is V1/V2, demeclocycline is used (not replaced), and tolvaptan is oral.
Question 3 of 5
All the following are true about penicillins EXCEPT:
Correct Answer: D
Rationale: Penicillins are safe in pregnancy, cross the BBB in meningitis, and are prolonged by probenecid, but they’re not mixed with aminoglycosides in one bolus due to inactivation; they’re given separately.
Question 4 of 5
An antimicrobial that is better to be avoided in patients with myasthenia gravis?
Correct Answer: A
Rationale: Gentamicin (aminoglycoside) exacerbates myasthenia gravis by impairing neuromuscular transmission, unlike rifampicin, ampicillin, or tetracycline.
Question 5 of 5
The following statements about rifampicin are true Except:
Correct Answer: B
Rationale: Rifampicin inhibits RNA polymerase, causes red urine, and induces CYP450 (reducing drug levels), but it’s not typically used for meningitis (isoniazid, others preferred).