ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
Albendazole is less effective than mebendazole in the following helminthic infestation
Correct Answer: B
Rationale: Albendazole is less effective than mebendazole for trichuriasis (whipworm), though it’s preferred for hydatid disease.
Question 2 of 5
Select the drug used in the treatment of filariasis
Correct Answer: A
Rationale: Di
Question 3 of 5
Which of the following drugs is used for candidiasis treatment:
Correct Answer: C
Rationale: Miconazole is an azole antifungal effective against candidiasis by inhibiting ergosterol synthesis, while griseofulvin targets dermatophytes, nitrofungin is less common, and streptomycin is an antibiotic.
Question 4 of 5
Azoles have an antifungal effect because of:
Correct Answer: C
Rationale: Azoles (e.g., miconazole, ketoconazole) inhibit 14-α-demethylase, reducing ergosterol synthesis, which disrupts fungal cell membrane integrity.
Question 5 of 5
All of the following drugs demonstrate a fungicidal effect, EXCEPT:
Correct Answer: D
Rationale: Terbinafine, amphotericin B, and ketoconazole are fungicidal, killing fungi. Miconazole is typically fungistatic, inhibiting growth rather than killing, though it can be fungicidal at high doses.