ATI RN
ATI Practice Exam Pharmacology The Hematologic System Questions
Question 1 of 5
Age associated changes in pharmacokinetics include:
Correct Answer: A
Rationale: Aging reduces creatinine clearance in about two-thirds of individuals due to declining renal function, a true statement impacting drug excretion. Body fat increases, not decreases, with age, altering distribution of lipophilic drugs, so that's false. Total body water decreases, not increases, affecting hydrophilic drugs. Conjugation (phase II) is less affected than oxidation (phase I) by age, making that false. Absorption isn't significantly altered by age alone. Reduced renal clearance is a critical age-related change, necessitating dose adjustments for renally cleared drugs like digoxin.
Question 2 of 5
Following ingestion, a drug crosses a membrane from an area of higher concentration to an area of lower concentration. This is an example of
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
The patient has been treated by the same physician for 2 years and has had insomnia the entire time. Many different medications have been tried with limited success. What should be the nurse's primary assessment at this time?
Correct Answer: A
Rationale: Persistent insomnia despite meds suggests a primary disorder like sleep apnea-e.g., obstructed breathing disrupts sleep-needing assessment (e.g., EEG), not just med failure. Selling meds lacks evidence. Addiction or personality disorders don't explain resistance. Sleep apnea fits chronicity, per sleep science.
Question 4 of 5
The nurse teaches a class for college students about osteoporosis. What is the best information to include?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
A 43-year-old Caucasian woman complains that her irises have been darkening. She says that she has been taking a drug for years to treat her glaucoma. Which of the following drugs is most likely causing the increased pigmentation of her irises?
Correct Answer: C
Rationale: Iris darkening in glaucoma treatment points to Latanoprost , a prostaglandin analog. It increases melanin in iridial melanocytes, a known side effect. Acetazolamide , a carbonic anhydrase inhibitor, Epinephrine , Pilocarpine , and Timolol (E) don't cause this. Latanoprost's cosmetic effect is well-documented, fitting her long-term use.