ATI RN
Microbiology A Systems Approach Test Bank Questions
Question 1 of 9
After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?
Correct Answer: A
Rationale: The correct answer is A: Rifampicin. Rifampicin is known to cause red discoloration of bodily fluids, including tears and urine, due to its side effect of harmless color changes. Benzylpenicillins (B and C) and Biseptol-480 do not typically cause such discoloration. Rifampicin's mechanism of action involves binding to bacterial RNA polymerase, leading to inhibition of RNA synthesis, which is unrelated to the mechanism of the other drugs. Thus, based on the unique side effect profile of Rifampicin and its mechanism of action, it is the most likely drug causing red tears and urine in this scenario.
Question 2 of 9
Two weeks after hemotransfusion a patient developed fever. What protozoal disease can be suspected?
Correct Answer: A
Rationale: The correct answer is A: Malaria. Two weeks after hemotransfusion, the onset of fever indicates a possible bloodborne infection. Malaria is a protozoal disease transmitted through infected blood, causing symptoms like fever. Toxoplasmosis, Leishmaniasis, and Amebiasis are not typically associated with fever following hemotransfusion. Malaria fits the timeline and mode of transmission in this scenario.
Question 3 of 9
The antigen receptors on the surface of B-lymphocytes are made by proteins:
Correct Answer: A
Rationale: The correct answer is A: TRUE. B-lymphocyte antigen receptors are made by proteins called immunoglobulins. These proteins are essential for recognizing and binding to specific antigens. They play a crucial role in the immune response. Choice B is incorrect because B-lymphocyte antigen receptors are indeed made by proteins. Choice C is incorrect as well because in this case, the correct answer is that the receptors are made by proteins. Choice D is also incorrect as the receptors are made by proteins.
Question 4 of 9
A patient with a severe sore throat had a throat culture revealing Gram-positive cocci in chains. The bacteria were beta-hemolytic. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pyogenes. This bacterium is the most likely causative agent due to its characteristic features. Streptococcus pyogenes is Gram-positive cocci in chains, which matches the description provided in the question. It is also known to be beta-hemolytic, causing complete lysis of red blood cells on blood agar. Streptococcus pyogenes is a common pathogen causing sore throat, often associated with pharyngitis. Explanation for incorrect choices: B: Streptococcus pneumoniae - This bacterium is Gram-positive but usually occurs in pairs (diplococci) and is alpha-hemolytic. C: Enterococcus faecalis - This bacterium is Gram-positive cocci but is not typically beta-hemolytic and is not commonly associated with sore throat infections. D: Staphylococcus aureus - This bacterium is Gram-positive cocci but usually occurs in clusters and
Question 5 of 9
How do people get infected with diphtheria
Correct Answer: C
Rationale: The correct answer is C because diphtheria is primarily spread through respiratory droplets and physical contact with an infected person. The bacteria responsible for diphtheria is transmitted through coughing, sneezing, or sharing personal items. Swimming in contaminated water (A) does not spread diphtheria. Transmission (B) is a broad term and does not specifically address the mode of transmission for diphtheria. Contaminated food (D) is not a typical route of diphtheria transmission. Therefore, option C is the most accurate choice based on the known mode of transmission for diphtheria.
Question 6 of 9
Microscopic analysis of a smear stained by Ziehl-Neelsen method revealed bright red bacilli. What microorganism is being tested for?
Correct Answer: A
Rationale: The Ziehl-Neelsen stain is specific for acid-fast bacteria like Mycobacterium tuberculosis. The bright red bacilli seen in the smear indicate the presence of acid-fast organisms, which is characteristic of Mycobacterium tuberculosis. Staphylococcus aureus, Clostridium tetani, and Escherichia coli are not acid-fast bacteria and would not be stained red using the Ziehl-Neelsen method. Therefore, the correct answer is A: Mycobacterium tuberculosis.
Question 7 of 9
Which of the following bacterial structures has endotoxic activity?
Correct Answer: A
Rationale: The correct answer is A: Lipopolysaccharides. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria and are known to have endotoxic activity. LPS can trigger a strong immune response leading to inflammation and septic shock. Choice B, Lipoproteins of Braun, are not known to have endotoxic activity. Choice C, Protein A, is a surface protein found in Staphylococcus aureus and is not associated with endotoxic activity. Choice D, None, is incorrect as LPS is indeed a bacterial structure with endotoxic activity.
Question 8 of 9
Which one is true for enteropathogenic E.coli?
Correct Answer: A
Rationale: The correct answer is A because enteropathogenic E. coli (EPEC) have fimbrial adhesins that help them bind to enterocytes in the intestines, leading to colonization and infection. This is a key virulence factor of EPEC. Explanation for why other choices are incorrect: B: EPEC typically cause watery diarrhea in infants, not bloody diarrhea similar to shigellosis. C: EPEC are not part of the normal intestinal flora; they are pathogenic bacteria. D: EPEC are not invasive and do not typically produce enterotoxin; they primarily adhere to the intestinal epithelium.
Question 9 of 9
Cholera is a serious gastrointestinal illness caused by bacteria of the genus:
Correct Answer: C
Rationale: The correct answer is C: Vibrio. Cholera is caused by Vibrio cholerae bacteria. These bacteria produce a toxin that causes severe diarrhea and dehydration. Escherichia (choice A) and Salmonella (choice B) are known for causing other types of gastrointestinal infections but not cholera. Acinetobacter (choice D) typically causes respiratory infections, not gastrointestinal illnesses like cholera. Therefore, the correct choice is Vibrio as it is specifically associated with cholera.