After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?

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Microbiology A Systems Approach Test Bank Questions

Question 1 of 9

After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?

Correct Answer: A

Rationale: The correct answer is A: Rifampicin. Rifampicin is known to cause red discoloration of bodily fluids, including tears and urine, due to its side effect of harmless color changes. Benzylpenicillins (B and C) and Biseptol-480 do not typically cause such discoloration. Rifampicin's mechanism of action involves binding to bacterial RNA polymerase, leading to inhibition of RNA synthesis, which is unrelated to the mechanism of the other drugs. Thus, based on the unique side effect profile of Rifampicin and its mechanism of action, it is the most likely drug causing red tears and urine in this scenario.

Question 2 of 9

What is the primary purpose of a bacterial capsule?

Correct Answer: C

Rationale: The correct answer is C: Enhancing virulence by preventing phagocytosis. Bacterial capsules help bacteria evade the immune system by preventing phagocytosis, a process where immune cells engulf and destroy pathogens. This enhances the bacteria's virulence and ability to cause infections. Choices A, B, and D are incorrect because bacterial capsules do not directly contribute to protein synthesis, protect against desiccation, or facilitate motility.

Question 3 of 9

The branch of pharmacology that addresses drug amounts at various sites in the body after drug administration is called:

Correct Answer: B

Rationale: The correct answer is B: pharmacokinetics. Pharmacokinetics is the study of drug movement in the body, including absorption, distribution, metabolism, and excretion. It focuses on how the body processes a drug over time. Pharmacodynamics (A) is the study of the effects drugs have on the body. Pharmacotherapeutics (C) involves using drugs to treat diseases. Pharmacy (D) is the practice of preparing and dispensing medications. Pharmacokinetics specifically deals with drug concentrations at different body sites after administration, making it the most appropriate choice for this question.

Question 4 of 9

The dynamic balance of the species in the normal microflora is known as

Correct Answer: D

Rationale: The correct answer is D: eubiosis. Eubiosis refers to a state of balance and harmony among the species in the normal microflora. This term signifies a healthy and stable microbial community. Dysbiosis (A) is the opposite, indicating an imbalance or disruption in the microflora. Eukaryota (B) refers to organisms with cells containing a nucleus, not specifically related to the balance of microflora. Dispersion (C) refers to the spreading or distribution of microorganisms, not specifically related to their balance. In summary, eubiosis best describes the dynamic balance of species in the normal microflora, making it the correct choice.

Question 5 of 9

Which of the following bacteria is responsible for causing the disease known as leprosy?

Correct Answer: A

Rationale: Step-by-step rationale: 1. Mycobacterium leprae is the correct answer because it is the bacterium responsible for causing leprosy. 2. Neisseria gonorrhoeae causes gonorrhea, not leprosy. 3. Escherichia coli is associated with gastrointestinal infections, not leprosy. 4. Staphylococcus aureus causes various skin infections, but not leprosy. In summary, Mycobacterium leprae is the correct choice because it is the specific bacterium known to cause leprosy, while the other options are associated with different diseases.

Question 6 of 9

Which of the following microorganisms require a moist environment to survive and most often live in ponds, streams, lakes, and oceans?

Correct Answer: D

Rationale: The correct answer is D: Blastospores. Blastospores are a type of fungal spore that requires a moist environment to survive. They are commonly found in water bodies like ponds, streams, lakes, and oceans. Mycorrhizae (A) are symbiotic associations between fungi and plant roots, not solely dependent on a moist environment. Armillaria gallica (B) is a type of fungus that can survive in various environmental conditions, not specifically reliant on a moist environment. Choice C is a duplicate of Blastospores, making it incorrect.

Question 7 of 9

Two weeks after hemotransfusion a patient developed fever. What protozoal disease can be suspected?

Correct Answer: A

Rationale: The correct answer is A: Malaria. Two weeks after hemotransfusion, the onset of fever indicates a possible bloodborne infection. Malaria is a protozoal disease transmitted through infected blood, causing symptoms like fever. Toxoplasmosis, Leishmaniasis, and Amebiasis are not typically associated with fever following hemotransfusion. Malaria fits the timeline and mode of transmission in this scenario.

Question 8 of 9

Bacteria capable of growing at low temperatures are called:

Correct Answer: C

Rationale: The correct answer is C: psychrophiles. Psychrophiles are bacteria that can grow at low temperatures, typically below 20°C. This is because they have adapted to survive and thrive in cold environments. Mesophiles (A) grow best at moderate temperatures, thermophiles (B) thrive in high temperatures, and halophiles (D) prefer high salt concentrations. Psychrophiles are specifically adapted to cold temperatures, making them the correct choice in this scenario.

Question 9 of 9

What is the name of the enzyme that allows the bacteria to become resistant to most penicillins?

Correct Answer: C

Rationale: The correct answer is C: Beta lactamase. This enzyme is produced by bacteria to break down the beta-lactam ring structure of penicillins, rendering them ineffective. Beta lactam ring (A) is part of the penicillin molecule, not an enzyme. MRSA (B) stands for methicillin-resistant Staphylococcus aureus, a type of bacteria resistant to certain antibiotics, not an enzyme. Aminoglycoside ring (D) refers to a different class of antibiotics and is not related to penicillin resistance in bacteria.

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