ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 5
Advise patient to avoid taking antacids or antidiarrheals for how long after taking digoxin?
Correct Answer: C
Rationale: Antacids or antidiarrheals should be avoided for at least 4 hours after taking digoxin. These medications can interfere with the absorption of digoxin in the body, thereby reducing its effectiveness. By spacing out the administration of these medications, the risk of decreased digoxin absorption and potential impact on its therapeutic effects can be minimized. It is important for patients to follow this guidance to ensure optimal effectiveness of digoxin therapy.
Question 2 of 5
The ulcerogenic properties of aspirin is caused by the following, except
Correct Answer: B
Rationale: The ulcerogenic properties of aspirin are primarily caused by the inhibition of prostaglandin synthesis, particularly through the inhibition of the enzyme cyclooxygenase-1 (Cox-1). Prostaglandins play a crucial role in maintaining the protective mucus barrier in the stomach lining. When prostaglandin synthesis is inhibited, this protective barrier is compromised, leading to increased susceptibility to damage from the acidic gastric environment. The drug's acidity itself (Choice A), by irritating the stomach lining, can contribute to ulcer formation. Thromboxane inhibition (Choice B) is not directly related to the ulcerogenic properties of aspirin but is more associated with the drug's antiplatelet effects. Cox-1 inhibition (Choice D) is a key factor in aspirin-induced gastrointestinal injury as it disrupts the normal mucosal defense mechanisms.
Question 3 of 5
A patient who has been diagnosed with social anxiety disorder will begin taking venlafaxine(Effexor). The nurse who performs a medication and dietary history will be concerned about ingestion of which substance or drug?
Correct Answer: D
Rationale: St. John's wort is an herbal supplement that can interact with many medications, including venlafaxine (Effexor). When taken together, it can decrease the effectiveness of venlafaxine by increasing its metabolism, potentially leading to reduced therapeutic effects. This interaction can also increase the risk of side effects or adverse reactions. Therefore, the nurse should be concerned about the ingestion of St. John's wort when a patient is taking venlafaxine to ensure proper medication management and effectiveness. It is important for patients to inform healthcare providers about all supplements they are taking to prevent harmful interactions.
Question 4 of 5
Which activity has a higher priority for the nurse to advise the patient to avoid while taking ixazomib?
Correct Answer: C
Rationale: Ixazomib, a proteasome inhibitor, can cause myelosuppression, increasing the risk of infections. Patients should be advised to avoid crowds and individuals who are ill to reduce exposure to infectious agents. While alcohol and aspirin may interact with other medications, they are not specifically contraindicated with ixazomib. Taking the drug on an empty stomach is not required, as it can be taken with or without food. Preventing infections is the highest priority due to the drug's impact on the immune system.
Question 5 of 5
A male patient is to begin therapy with isotretinoin and asks, 'What do I have to remember to do while taking this medicine?' How would the nurse respond? (Select all that apply.)
Correct Answer: B
Rationale: Isotretinoin is a potent medication with significant side effects and precautions. Patients should avoid sunlight (A) due to increased photosensitivity. Regular laboratory tests (C) are necessary to monitor liver function and lipid levels. Two forms of contraceptives (D) are required for females due to the high risk of teratogenicity. Monitoring weight (B) is not typically associated with isotretinoin use.