ATI RN
Endocrine Pharmacology Quiz Questions
Question 1 of 5
Adverse effects associated with the combined oral contraceptive include:
Correct Answer: B
Rationale: Combined oral contraceptives increase stroke risk in migraineurs and can cause Budd-Chiari syndrome (hepatic vein thrombosis). Other effects are less directly linked.
Question 2 of 5
For patients who have been on long-term therapy with a glucocorticoid and who now wish to discontinue the drug, gradual tapering of the glucocorticoid is needed to allow recovery of
Correct Answer: D
Rationale: Tapering prevents adrenal insufficiency by allowing the HPA axis to recover from suppression.
Question 3 of 5
All of the following conditions are causes of hypothyroidism except
Correct Answer: D
Rationale: Graves' disease causes hyperthyroidism, not hypothyroidism.
Question 4 of 5
A 29-year-old man with a family history of heart disease presents to his primary care physician for a routine checkup. A lipid profile on a blood draw reveals high LDL and low HDL. One way to decrease the amount of LDL in the blood is to hinder the liver's ability for de novo cholesterol synthesis. Which of the following drugs blocks de novo cholesterol synthesis in hepatocytes?
Correct Answer: D
Rationale: Rosuvastatin, an HMG-CoA reductase inhibitor (statin), blocks de novo cholesterol synthesis in the liver by inhibiting the rate-limiting enzyme, reducing LDL levels.
Question 5 of 5
A 58-year-old man with depression who takes a monoamine oxidase inhibitor has a love for aged cheese and wine. His depression is well controlled in this regimen. He must be alert to which of the following significant events?
Correct Answer: B
Rationale: MAOIs inhibit tyramine metabolism; aged cheese and wine are high in tyramine, which can cause a hypertensive crisis (headaches) due to catecholamine release.