Adrenaline is contraindicated in:

Correct Answer: D

Rationale: Adrenaline is contraindicated in hypertension because it can worsen high blood pressure and increase the risk of cardiovascular events. Adrenaline's vasoconstrictive effects can further elevate blood pressure in individuals with hypertension, potentially leading to severe complications. Therefore, it is crucial to avoid administering adrenaline in patients with hypertension to prevent adverse cardiovascular outcomes. Summary: - A: Adrenaline is indicated in cardiac arrest to improve cardiac output. - B: Adrenaline is indicated in acute bronchial asthma to relax bronchial smooth muscles. - C: Adrenaline is indicated in anaphylactic shock to reverse severe allergic reactions. - D (Correct): Adrenaline is contraindicated in hypertension due to its vasoconstrictive effects.

Correct Answer: D

Rationale: The correct answer is D: Atropine does not produce bronchoconstriction. Atropine is an anticholinergic drug that blocks the action of acetylcholine, leading to increased heart rate (A), stimulation of the respiratory center (B), and mydriatic effect (C). Bronchoconstriction is not a pharmacological effect of atropine because it actually helps dilate the bronchi, making it a useful treatment in cases of bronchospasm.

Correct Answer: D

Rationale: The correct answer is D because acidification of urine actually increases the excretion of amphetamine. Step 1: Amphetamine is an indirect acting sympathomimetic, which means it stimulates the release of norepinephrine. Step 2: It has prominent CNS action by increasing the release of dopamine and norepinephrine, leading to effects like increased alertness and euphoria. Step 3: Chronic use of amphetamine can indeed lead to addiction due to its reinforcing properties and impact on the brain's reward system. Therefore, D is incorrect as acidification of urine does not decrease amphetamine excretion; instead, it can enhance excretion by increasing its solubility in urine.

Correct Answer: A

Rationale: Sumatriptan is the correct answer for treating acute migraine attacks as it is a specific serotonin receptor agonist that helps constrict blood vessels in the brain. Ergometrine and dihydroergometrine are ergot alkaloids used for other conditions, not migraine. Propranolol is a beta-blocker used for migraine prevention, not acute attacks.

Correct Answer: D

Rationale: Terbutaline specifically stimulates Beta2 receptors. This leads to bronchodilation by relaxing smooth muscles in the airways. Beta2 receptors are predominantly found in the lungs. Option A and B are incorrect as terbutaline does not target Alpha receptors. Option C is incorrect as terbutaline does not primarily stimulate Beta1 receptors, which are mainly found in the heart.