ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
Activates the complement system
Correct Answer: D
Rationale: Both IgG and IgM can activate the complement system via the classical pathway.
Question 2 of 5
Which of the following uses the enzyme horseradish peroxidase (HRP)?
Correct Answer: D
Rationale: Both ELISA and Western blotting commonly use horseradish peroxidase (HRP) as an enzyme for signal detection.
Question 3 of 5
Class switching (isotype switching) involves rearrangement of the V(H) exon to associate with a different C(H) exon at different times in the course of an immune response. The region of the antibody molecule is affected (changed) via class switching and, unlike somatic recombination, this process is antigen
Correct Answer: C
Rationale: Class switching affects the Fc region and is antigen-dependent, occurring after B cell activation.
Question 4 of 5
Which of the following best describes the location of the delta (δ)-chain locus in human T-cell receptors?
Correct Answer: D
Rationale: The delta (δ)-chain locus is located within the alpha (α)-locus on chromosome 14.
Question 5 of 5
Superantigens such as staphylococcal enterotoxins bind to certain TCR chains and to MHC class II molecules. MHC binding does not involve the peptide groove. T cells can then release extremely high levels of cytokines, which lead to toxic shock syndrome (TSS) when they appear in the blood.
Correct Answer: B
Rationale: Superantigens typically bind to TCR beta (β) chains and MHC class II, triggering massive cytokine release.