ATI RN
Basic Principles of Pharmacology Quizlet Questions
Question 1 of 5
Actions taken to reduce drug-drug interaction problems include all of the following EXCEPT:
Correct Answer: C
Rationale: The correct answer is C because prescribing a third drug to counteract the adverse reaction of the combination does not address the root cause of the drug-drug interaction. It may lead to further complications and potentially more interactions. Reducing the dose of one drug (A) or both drugs (D) and scheduling their administration at different times (B) are effective strategies to minimize drug-drug interactions by adjusting the dosing regimen.
Question 2 of 5
The major reason for not crushing a sustained release capsule is that, if crushed, the coated beads of the drugs could possibly result in:
Correct Answer: B
Rationale: The correct answer is B: Toxicity. Crushing a sustained-release capsule can disrupt the controlled release mechanism, leading to the rapid release of a potentially toxic dose. This can overwhelm the body's ability to metabolize the drug safely, causing toxicity. Disintegration (A) would not be the major concern as the beads would still release the drug. Malabsorption (C) is less likely as the drug would still be absorbed, albeit possibly too quickly. Deterioration (D) refers to physical changes in the drug, not toxicity.
Question 3 of 5
An advantage of prescribing a sublingual medication is that the medication is:
Correct Answer: A
Rationale: The correct answer is A: Absorbed rapidly. Sublingual medication is absorbed directly into the bloodstream through the mucous membranes under the tongue, bypassing the digestive system and liver first-pass metabolism. This route allows for faster onset of action and higher bioavailability compared to oral ingestion. Excretion rate (option B) and distribution pattern (option D) are not specific advantages of sublingual administration. While metabolism may be reduced (option C), the primary advantage is the rapid absorption.
Question 4 of 5
Up-regulation or hypersensitization may lead to:
Correct Answer: C
Rationale: The correct answer is C: An exaggerated response if the drug is withdrawn. Up-regulation or hypersensitization involves an increase in the number or sensitivity of receptors, leading to an intensified response when the drug is suddenly stopped. This occurs due to the heightened receptor activity and can result in withdrawal symptoms or rebound effects. Choices A and B are incorrect because up-regulation typically results in increased, not decreased, response to the drug. Choice D is incorrect as refractoriness or complete lack of response is more indicative of down-regulation or desensitization.
Question 5 of 5
When developing an effective medication teaching plan, which component will the nurse identify as most essential?
Correct Answer: B
Rationale: The correct answer is B: The patient’s readiness to learn. This is the most essential component because it determines the patient’s receptiveness and ability to understand and apply the medication teaching plan. Assessing the patient’s readiness ensures that the teaching is tailored to their individual needs and learning style, increasing the likelihood of successful medication management. A: Written instructions may be helpful but are not as effective if the patient is not ready to learn. C: Use of colorful charts can enhance understanding, but without considering the patient’s readiness, it may not be as impactful. D: Review of community resources is important but not as crucial as assessing the patient’s readiness to learn for effective medication teaching.