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Drugs Affecting the Female Reproductive System NCLEX Quizlet Questions
Question 1 of 5
Action of Insulin does not include the following:
Correct Answer: C
Rationale: The correct answer is C: Facilitation of neoglucogenesis by liver. Insulin's main role is to lower blood glucose levels by promoting glucose uptake into cells (A) and glycogen synthesis in the liver (B), and inhibiting lipolysis in adipose tissue (D). Neoglucogenesis is the process of synthesizing new glucose molecules, which is not a function of insulin. Therefore, choice C is incorrect as insulin does not facilitate neoglucogenesis.
Question 2 of 5
Insulin therapy is required for the following category/categories of type 2 diabetes mellitus patients:
Correct Answer: D
Rationale: Insulin therapy is required for patients with ketoacidosis to lower blood glucose levels. Patients undergoing surgery may need insulin to manage blood sugar fluctuations. Pregnant diabetics often require insulin to maintain stable blood sugar levels for fetal health. Therefore, the correct answer is D, as all the mentioned categories of type 2 diabetes patients may benefit from insulin therapy. Choices A, B, and C are incorrect because insulin therapy may be necessary for each of these specific patient groups due to their unique medical needs related to type 2 diabetes.
Question 3 of 5
The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they:
Correct Answer: D
Rationale: Step 1: Second generation sulfonylureas like glimepiride and glipizide are less likely to cause hypoglycemic reactions compared to first generation ones like chlorpropamide and tolbutamide. Step 2: This is because second generation drugs have a shorter duration of action and are more selective for pancreatic beta cells, reducing the risk of hypoglycemia. Step 3: Therefore, option D is correct as it accurately reflects the difference between the two generations in terms of hypoglycemic risk. Summary: - Option A is incorrect because both generations can be potent in lowering blood sugar. - Option B is incorrect as second generation drugs are not necessarily longer acting. - Option C is incorrect as sulfonylureas lower blood sugar regardless of the patient's diabetic status.
Question 4 of 5
The hypoglycaemic action of sulfonylureas is likely to be reduced by the concurrent use of:
Correct Answer: B
Rationale: The correct answer is B, Propranolol. Propranolol is a beta-blocker that can mask the symptoms of hypoglycemia, making it difficult to recognize and treat low blood sugar levels. This can lead to severe hypoglycemia if not properly managed. Hydrochlorothiazide (A) is a diuretic, Theophylline (C) is a bronchodilator, and Aspirin (D) is a pain reliever, none of which directly affect the hypoglycemic action of sulfonylureas.
Question 5 of 5
Choose the correct statement(s) about pioglitazone:
Correct Answer: D
Rationale: Step 1: Pioglitazone is a thiazolidinedione that acts as an agonist on nuclear peroxisome proliferator receptor γ (PPAR-γ). Step 2: Activation of PPAR-γ enhances transcription of insulin responsive genes. Step 3: By enhancing insulin sensitivity and glucose uptake in peripheral tissues, pioglitazone lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia. Step 4: Therefore, all the statements A, B, and C are correct, making option D the correct answer. Other choices are incorrect as they do not accurately describe the mechanism of action and effects of pioglitazone.