ATI RN
ATI Proctored Pharmacology 2024 Questions
Question 1 of 5
Action of fibrinolytic drugs
Correct Answer: C
Rationale: Fibrinolytic drugs act by promoting the breakdown of blood clots or thrombi. These drugs activate plasminogen, which is present in the blood, to form plasmin. Plasmin is an enzyme that directly breaks down fibrin, the main protein in blood clots, thus dissolving the clot and facilitating the restoration of blood flow in the affected area. This mechanism of action helps in treating conditions such as acute myocardial infarction (heart attack) and ischemic stroke, where rapid clot dissolution is crucial to prevent tissue damage.
Question 2 of 5
A patient has been diagnosed with tuberculosis and is to begin antitubercular therapy with isoniazid, rifampin, and ethambutol. Which actions are appropriate for the nurse to do? (Select all that apply.)
Correct Answer: A
Rationale: Ethambutol can cause optic neuritis, so periodic eye examinations are essential. Taking medications with meals can help reduce gastrointestinal side effects. Antacids should be avoided as they can interfere with drug absorption. Numbness and tingling of the hands or feet may indicate peripheral neuropathy, a side effect of isoniazid, and should be reported promptly.
Question 3 of 5
Beta-adrenergic blocking drugs are used in children for disorders similar to those in adults. What adrenergic blocking agent is used during surgery for pheochromocytoma?
Correct Answer: C
Rationale: Phentolamine is used during surgery for pheochromocytoma in children. Prazosin is used to treat hypertension in children. Propranolol and guanethidine are not indicated for use in children with a pheochromocytoma. The nurse should understand the indications for phentolamine to ensure safe and effective administration.
Question 4 of 5
A patient with type 2 diabetes mellitus asks the nurse how metformin decreases blood sugar. What is the best response by the nurse?
Correct Answer: A
Rationale: Metformin primarily works by decreasing hepatic glucose production and improving insulin sensitivity in peripheral tissues. It does not increase insulin resistance (B), block carbohydrate absorption (C), or stimulate insulin release (D). These mechanisms help lower blood glucose levels in patients with type 2 diabetes.
Question 5 of 5
A nurse is giving medicinal instructions to a female client receiving leflunomide (Arava). Which of the following is an appropriate instruction with the use of the medication?
Correct Answer: A
Rationale: Leflunomide is teratogenic and can cause severe birth defects. Women of childbearing age must use effective contraception during treatment and for a period after discontinuation. Breastfeeding is contraindicated due to the risk of harm to the infant. Cholestyramine is used to accelerate the elimination of leflunomide in case of toxicity, not to lessen side effects. Improvement in symptoms typically takes weeks, not days.