Absorption of oral iron preparations can be facili

ATI RN

ATI RN Test Bank

Absorption of oral iron preparations can be facilitated by coadministering

A. Antacids B. Tetracyclines C. Phosphates D. Ascorbic acid

Correct Answer: D

Rationale: Ascorbic acid (vitamin C) enhances iron absorption by reducing ferric to ferrous iron.

The percentage of elemental iron hydrated ferrous sulfate is

A. 5% B. 10% C. 20% D. 33%

Correct Answer: C

Rationale: Hydrated ferrous sulfate (FeSO4Â·7H2O) contains approximately 20% elemental iron by weight.

In isolated fibroblast or epithelial cells, retinoids enhance the synthesis of following protein

A. Fibronectin B. Collagenase C. Certain species of keratin D. All of the above

Correct Answer: A

Rationale: Retinoids specifically enhance fibronectin synthesis in fibroblasts and epithelial cells.

The side effect which primarily limits acceptability of oral iron therapy is

A. Epigastric pain and bowel upset B. Black stools C. Staining of teeth D. Metallic taste

Correct Answer: A

Rationale: Epigastric pain and bowel upset (e.g., nausea, constipation) are the primary reasons patients discontinue oral iron therapy.

Iron sorbitol-citric acid differs from iron dextran in that

A. It cannot be injected i.v. B. It is not excreted in urine C. It is not bound to transferritin in plasma D. It produces fewer side effects

Correct Answer: A

Rationale: Iron sorbitol-citric acid is for intramuscular use only, unlike iron dextran, which can be given IV.

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