A54-year-old man at a scheduled ophthalmic check-up was found to have increased intraocular pressure. The man had been suffering from open-angle glaucoma for 2 years, but up until the current visit, the disease was found to be well controlled by local treatment with timolol and latanoprost. Drugs taken recently by the patient included over-the-counter preparations for episodic headache, heartburn, and insomnia. Which of the following drugs could have caused the patient's increased intraocular pressure?

Correct Answer: D

Rationale: The correct answer is D: Diphenhydramine. Diphenhydramine is an anticholinergic drug that can cause an increase in intraocular pressure by dilating the pupil and affecting the eye's ability to drain fluid properly. The patient's increased intraocular pressure could be due to the use of diphenhydramine for insomnia. Acetaminophen (A), omeprazole (B), and ibuprofen (C) do not typically cause an increase in intraocular pressure. Acetaminophen is a pain reliever, omeprazole is a proton pump inhibitor used for heartburn, and ibuprofen is a nonsteroidal anti-inflammatory drug.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.