ATI RN
Pediatric Immunity NCLEX Questions Questions
Question 1 of 5
A young patient presents with severe infections from encapsulated bacteria and collagen vascular disease. Lab work confirms a diagnosis via CH50 and AP50. Which of the following is the most likely?
Correct Answer: D
Rationale: C3 deficiency impairs opsonization, leading to infections with encapsulated bacteria and immune complex diseases.
Question 2 of 5
Persons with helminth infections mount immunologic responses that involve IgE and eosinophils. Which two cytokines are most important for these responses to occur?
Correct Answer: B
Rationale: IL-4 promotes IgE production, and IL-5 enhances eosinophil development and activation, both critical for immune responses against helminths.
Question 3 of 5
Mutations in the gammac chain of the receptors for IL-2, 4, 7, 9 and 15 lead to?
Correct Answer: D
Rationale: Mutations in the common gamma chain (γc) disrupt signaling for multiple interleukins, causing severe combined immunodeficiency (SCID).
Question 4 of 5
When a human pathogen is repeatedly grown and passaged in cells of a different species and then used for vaccination purposes, the resulting vaccine is referred to as a/an...?
Correct Answer: D
Rationale: Passaging a pathogen in a different species attenuates it, creating a live attenuated vaccine, as seen with some viral vaccines.
Question 5 of 5
The first immunoglobulin heavy chain class to be expressed on the surface of a newly produced B-cell is...?
Correct Answer: D
Rationale: IgM is the first immunoglobulin expressed on naive B cells, followed by co-expression with IgD during maturation.