A young couple presented to the physician complaining that they have been trying for 2 years to conceive a second child but have not been successful. Their first child was a healthy 4-year-old girl. Lab tests revealed that the husband was severely oligospermic. On questioning, he admitted he had been taking some drugs to aid his athletic performance. Which of the following drugs most likely contributed to the oligospermia of this man?

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Endocrine Pharmacology NCLEX Questions Questions

Question 1 of 5

A young couple presented to the physician complaining that they have been trying for 2 years to conceive a second child but have not been successful. Their first child was a healthy 4-year-old girl. Lab tests revealed that the husband was severely oligospermic. On questioning, he admitted he had been taking some drugs to aid his athletic performance. Which of the following drugs most likely contributed to the oligospermia of this man?

Correct Answer: B

Rationale: The correct answer is B: Danazol. Danazol is an androgen derivative that can suppress testosterone production, leading to oligospermia. This drug is known to have negative effects on sperm production and fertility. In this case, the husband's use of drugs to aid athletic performance likely included danazol, which contributed to his oligospermia. Choice A: Vitamin B12 is not known to cause oligospermia. It is essential for sperm production and overall reproductive health. Choice C: Ferrous sulphate is a form of iron supplement and is not associated with oligospermia. It is used to treat iron deficiency anemia. Choice D: Medroxyprogesterone is a progestin hormone and is not a known cause of oligospermia. It is used for various medical conditions but does not directly impact sperm production.

Question 2 of 5

Which one of the following hormones not synthesized in the hypothalamus?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Glucocorticoids:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

All are true except: Post-coital contraception consisting of levonorgestrol given within 72 hours of unprotected intercourse:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Rapid withdrawal after prolonged prednisolone administration can cause all the following except:

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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