A young child undergoes implantation of a cardiac pacemaker. During surgery, the physician must remove the thymus. If this child encounters an antigen requiring B-cell-Tcell collaboration, they will to mount an immune response. These antigens are thus called

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Pediatric Immunization Test Questions Questions

Question 1 of 5

A young child undergoes implantation of a cardiac pacemaker. During surgery, the physician must remove the thymus. If this child encounters an antigen requiring B-cell-Tcell collaboration, they will to mount an immune response. These antigens are thus called

Correct Answer: C

Rationale: Thymectomy prevents T cell development, impairing responses to thymus-dependent antigens.

Question 2 of 5

Antigens and lymphoid cells are delivered to the secondary lymphoid tissues (spleen, lymph nodes) via:

Correct Answer: D

Rationale: Dendritic cells are key antigen-presenting cells delivering antigens to secondary lymphoid tissues.

Question 3 of 5

Which of the following is a low affinity antibody?

Correct Answer: D

Rationale: IgM has low affinity due to its pentameric structure and initial response role.

Question 4 of 5

Low pH

Correct Answer: C

Rationale: Low pH in the GI tract (e.g., stomach acid) is an innate barrier.

Question 5 of 5

In the classical complement pathway, which of the following components is the initiating protein(s)?

Correct Answer: A

Rationale: C1 is the initiating protein in the classical pathway, binding to antibodies.

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