A wound swab from a patient with a deep tissue infection revealed Gram-positive rods with terminal spores. What is the most likely causative agent?

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Question 1 of 5

A wound swab from a patient with a deep tissue infection revealed Gram-positive rods with terminal spores. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Clostridium perfringens. This is because Clostridium perfringens is a Gram-positive rod bacterium that forms terminal spores. It is commonly associated with deep tissue infections and can cause gas gangrene. Bacillus anthracis (B) causes anthrax and does not typically form spores at the terminal end. Clostridium tetani (C) causes tetanus and Bacillus cereus (D) is more commonly associated with food poisoning. In this case, the presence of terminal spores along with the clinical presentation of a deep tissue infection points towards Clostridium perfringens as the most likely causative agent.

Question 2 of 5

Which bacteria produce exotoxins that can cause severe dehydration and diarrhea?

Correct Answer: A

Rationale: The correct answer is A: Vibrio cholerae. This bacterium produces cholera toxin, an exotoxin that causes severe dehydration and diarrhea by increasing the secretion of electrolytes and water in the intestines. Vibrio cholerae is the causative agent of cholera, a disease characterized by profuse watery diarrhea. Choice B, Clostridium tetani, produces tetanospasmin causing tetanus, not dehydration or diarrhea. Choice C, Escherichia coli, can cause diarrhea but rarely severe dehydration. Choice D, Shigella dysenteriae, produces Shiga toxin leading to bloody diarrhea, not severe dehydration.

Question 3 of 5

A wound infection culture revealed Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-negative. What is the most likely causative agent?

Correct Answer: A

Rationale: The most likely causative agent in this case is Staphylococcus epidermidis. This conclusion can be drawn based on the characteristics provided: Gram-positive cocci in clusters, catalase-positive, and coagulase-negative. Staphylococcus epidermidis fits all these criteria. Explanation of other choices: - Staphylococcus aureus: Typically coagulase-positive, so it does not match the characteristics given. - Streptococcus pyogenes: Gram-positive cocci in chains, not clusters. Also, it is catalase-negative. - Enterococcus faecalis: Gram-positive cocci in pairs or chains, not clusters. Additionally, it is catalase-negative. Therefore, Staphylococcus epidermidis is the most likely causative agent based on the provided characteristics.

Question 4 of 5

A patient with pneumonia had sputum cultured, revealing Gram-negative rods. The bacteria were lactose fermenters and produced green colonies on MacConkey agar. What is the most likely causative agent?

Correct Answer: A

Rationale: Rationale: 1. Gram-negative rods suggest Enterobacteriaceae family. 2. Lactose fermenters narrow down to E. coli. 3. Green colonies on MacConkey agar indicate acid production. 4. E. coli is a common cause of pneumonia. Therefore, the most likely causative agent is Escherichia coli. Other choices are incorrect as Klebsiella is non-lactose fermenter, Pseudomonas is oxidase-positive, and Proteus is non-lactose fermenter.

Question 5 of 5

Which of the following bacteria is responsible for causing peptic ulcers?

Correct Answer: B

Rationale: The correct answer is B: Helicobacter pylori. This bacterium is known to be the primary cause of peptic ulcers by colonizing the stomach lining and causing inflammation. It produces urease enzyme to neutralize stomach acid and has a flagellum for mobility. Escherichia coli (A) is mainly associated with foodborne illnesses. Streptococcus pyogenes (C) causes strep throat and skin infections. Mycobacterium tuberculosis (D) causes tuberculosis, a respiratory infection. Therefore, Helicobacter pylori is the correct choice for peptic ulcers based on its unique characteristics and pathogenicity.

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