A wound culture from a patient with an infected ulcer revealed Gram-positive rods with terminal spores. What is the most likely causative agent?

Correct Answer: A

Rationale: Step-by-step rationale: 1. Gram-positive rods with terminal spores suggest Clostridium genus. 2. Terminal spores are characteristic of Clostridium perfringens. 3. C. perfringens is known to cause wound infections. 4. Therefore, the most likely causative agent is Clostridium perfringens. Summary: A: Clostridium perfringens is correct due to its characteristic features and association with wound infections. B: Bacillus anthracis does not typically form terminal spores. C: Clostridium tetani causes tetanus, not wound infections. D: Bacillus cereus does not produce terminal spores like Clostridium perfringens.

Correct Answer: A

Rationale: Step-by-step rationale: 1. IgG is the most abundant immunoglobin in a normal healthy adult due to its long half-life and diverse functions. 2. It plays a crucial role in immune response by neutralizing pathogens and enhancing phagocytosis. 3. IgA is mainly found in mucosal areas, IgE is involved in allergic reactions, and IgD's function is not fully understood. 4. Therefore, IgG is the correct answer as it is the predominant immunoglobin in circulation, providing broad immune protection.

Correct Answer: B

Rationale: The correct answer is B: Contains single-stranded RNA with negative polarity. Measles virus is an enveloped virus with a single-stranded RNA genome that is negative-sense. This means it must first be transcribed into positive-sense RNA before it can be translated. Choice A is incorrect as the measles virus does have an outer envelope. Choice C is incorrect as measles virus belongs to the family Paramyxoviridae, not Togaviridae. Choice D is incorrect as measles virus can be grown on cell cultures, specifically on Vero cells.

Correct Answer: A

Rationale: The most probable diagnosis is A: Candidous cheilitis. Candidous cheilitis is a fungal infection caused by Candida species. In this case, the presence of mycelium on the plaques indicates a fungal infection. The symptoms of pain, burning, and grey plaques that can be easily removed leaving hyperemia are typical for Candidous cheilitis. Choice B (Exfoliative cheilitis) is characterized by scaling and peeling of the lips, not plaques with mycelium. Choice C (Leukoplakia) is a precancerous condition causing white plaques that cannot be easily removed. Choice D (Contactant allergic cheilitis) is an allergic reaction causing inflammation, not fungal plaques.

Correct Answer: A

Rationale: The correct answer is A: epidermis. Langerhans cells are a type of immune cell found in the epidermis, the outermost layer of the skin. They play a crucial role in the defense against microbes by capturing and presenting antigens to activate the immune system. The dermis (B), hypodermis (C), and subcutaneous layer (D) are located deeper in the skin and do not contain Langerhans cells. Therefore, the epidermis is the correct location for these immune cells to carry out their defensive functions.

Correct Answer: D

Rationale: The correct answer is D: Hypersensitivity of delayed type. The symptoms described occur 5-10 days after exposure to the antigen, consistent with a delayed hypersensitivity reaction. This type of reaction involves T cells and is characterized by cell-mediated immune response, leading to inflammation and tissue damage. Choices A, B, and C are incorrect because they are associated with different mechanisms of allergic reactions. Immunocomplex reactions (choice A) involve antigen-antibody complexes depositing in tissues, immediate hypersensitivity reactions (choice B) involve IgE-mediated mast cell degranulation, and cytotoxic reactions (choice C) involve antibodies targeting specific cells for destruction.

Correct Answer: A

Rationale: The correct answer is A because the cytoplasmic membrane in bacteria is primarily composed of phospholipids, glycerol, and glycolipids. Phospholipids form the basic structure of the membrane, with glycerol serving as the backbone and glycolipids present on the outer surface. Lipopolysaccharides (choice B) are primarily found in the outer membrane of Gram-negative bacteria, not the cytoplasmic membrane. Choice C is incorrect because peptidoglycan is a component of the bacterial cell wall, not the cytoplasmic membrane. Choice D is incorrect as the cytoplasmic membrane in bacteria is indeed composed of phospholipids, glycerol, and glycolipids.

Correct Answer: B

Rationale: The correct answer is B: H antigen. Flagellar antigen is typically referred to as the H antigen in bacteria. Flagella are the whip-like structures used for movement in bacteria, and the H antigen is specifically associated with the flagella. The other choices (A: D antigen, C: K antigen, D: F antigen) are not related to flagella in bacteria and are commonly associated with other types of antigens in bacterial classification.

Correct Answer: A

Rationale: Neisseria gonorrhoeae is the correct answer because it is the specific bacterium responsible for causing gonorrhea. It is a sexually transmitted infection that primarily affects the genital tract. Neisseria gonorrhoeae is transmitted through sexual contact and can lead to symptoms such as painful urination, discharge, and pelvic pain. Chlamydia trachomatis (Choice B) is another sexually transmitted bacterium, but it causes chlamydia, not gonorrhea. Mycobacterium tuberculosis (Choice C) is responsible for tuberculosis, a different infectious disease that primarily affects the lungs. Treponema pallidum (Choice D) causes syphilis, another sexually transmitted infection that presents with distinct symptoms from gonorrhea. Therefore, Neisseria gonorrhoeae is the correct choice for causing gonorrhea due to its specific association with this particular infection.