ATI RN
ATI Pharmacology Practice Exam B Questions
Question 1 of 5
A woman who wishes to become pregnant is concerned about the drugs she must take in order to treat a serious medical condition. The nurse reviewing the drug list would be most concerned about which kind of drug?
Correct Answer: A
Rationale: Long half-life drugs (e.g., diazepam) linger, risking fetal exposure post-conception, a pharmacokinetic worry for serious conditions. No active metabolites reduce risk. High protein-binding limits free drug, less concern. As-needed use minimizes exposure. Long half-life heightens teratogenic potential, critical in planning.
Question 2 of 5
An 18-year-old woman presents to her primary care physician after experiencing a one-sided headache for the fourth time in the last 2 years. Her headaches have all been similar in nature. She says the pain is worst right behind her eye and that she feels nauseous and cannot stand bright lights or loud noises while she is having a headache. The physician prescribes sumatriptan. What is the mechanism of action of this medication?
Correct Answer: B
Rationale: Migraine symptoms (unilateral pain, photophobia, nausea) respond to sumatriptan, a 5-HT1B/1D agonist. Option , blocking serotonin-mediated nociceptive signaling, is correct-sumatriptan constricts cranial vessels and inhibits trigeminal pain pathways. Option , COX blockade, is NSAIDs' mechanism. Option , prostaglandin synthesis, is similar. Options and (E), opioid receptor stimulation, are unrelated. Sumatriptan's serotonin action targets migraine-specific pathophysiology, relieving this patient's symptoms.
Question 3 of 5
A 31-year-old woman smoker expresses a desire to quit smoking. She has a 10 pack-year history of smoking but no other health issues. She wants to try varenicline, a drug she recently heard about, to help her quit. Which of the following side effects of varenicline is she most likely to encounter?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A 13-year-old boy with moderate asthma presents to the clinic for follow-up. His symptoms appear to be better controlled since adding salmeterol to his regimen. He has had to use his rescue inhaler once over the past 2 weeks during exertion. His breathing at night has improved as well. How does salmeterol exhibit its beneficial effects for asthma?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Which of the following antipsychotic agents is available in a LAI formulation that may be useful for patients with difficulty adhering to therapy?
Correct Answer: D
Rationale: Risperidone, a second-generation antipsychotic, offers a long-acting injectable (LAI) formulation (e.g., Risperdal Consta), administered every two weeks, improving adherence in schizophrenia patients with poor oral compliance. Asenapine is sublingual, not LAI. Chlorpromazine, a first-generation drug, lacks an LAI form. Clozapine, effective for treatment-resistant cases, is oral only due to agranulocytosis monitoring. Quetiapine has no LAI. Risperidone's LAI ensures steady drug levels, reducing relapse risk, making it ideal for adherence challenges, per clinical use.